{"id":"W2891401984","doi":"10.1038/s41467-018-06341-8","title":"RARα supports the development of Langerhans cells and langerin-expressing conventional dendritic cells","year":2018,"lang":"en","type":"article","venue":"Nature Communications","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics; National Institute of Diabetes and Digestive and Kidney Diseases; U.S. Department of Health and Human Services; National Institutes of Health; School of Medicine, Indiana University; National Institute of Allergy and Infectious Diseases; Division of Intramural Research, National Institute of Allergy and Infectious Diseases; Purdue University","keywords":"Langerin; Cell biology; Dendritic cell; Langerhans cell; Biology; Immunology; Immune system","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001897601,0.0002432799,0.0001770501,0.0002137273,0.0001145459,0.0003989179,0.000148418,0.0001730969,0.001285689],"category_scores_gemma":[0.0001293303,0.0001074924,0.0001431845,0.00009333407,0.0002767916,0.0001798453,0.0002221459,0.0004576748,0.0007330889],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000236751,"about_ca_system_score_gemma":0.00021231,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003176169,"about_ca_topic_score_gemma":0.0004679202,"domain_scores_codex":[0.9997795,0.00004094932,0.00002054632,0.00004026911,0.00007086468,0.00004787898],"domain_scores_gemma":[0.9997264,0.00004262582,0.00007543343,0.00005357516,0.00003220937,0.00006981051],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000540998,0.000009931585,0.0002236868,0.00001251343,0.000001021515,0.0000360259,0.000009372256,0.00001643192,0.9989347,0.00008318399,0.00002158265,0.0005975065],"study_design_scores_gemma":[0.00001653907,0.0001941465,0.007386194,0.000007495611,0.00000726783,0.0002915902,0.00005544357,0.0003674772,0.987407,0.0001087175,0.004155896,0.000002162723],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9906474,0.002620679,0.002856919,0.0001073638,0.00003623169,0.00002380587,0.000330961,0.0001222176,0.003254416],"genre_scores_gemma":[0.9941667,0.0006336893,0.00133313,0.00003545533,0.00002343848,0.00001662251,0.0003244679,0.00002257623,0.003443778],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001285689,"threshold_uncertainty_score":0.004301131,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01710267037903071,"score_gpt":0.2799005284828883,"score_spread":0.2627978581038576,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}