{"id":"W2891576771","doi":"10.1016/s1470-2045(18)30456-x","title":"Effect of apalutamide on health-related quality of life in patients with non-metastatic castration-resistant prostate cancer: an analysis of the SPARTAN randomised, placebo-controlled, phase 3 trial","year":2018,"lang":"en","type":"article","venue":"The Lancet Oncology","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":128,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"Janssen Research and Development","keywords":"Medicine; Androgen deprivation therapy; Prostate cancer; Placebo; Clinical endpoint; Internal medicine; Prostate-specific antigen; Oncology; Randomized controlled trial; Urology; Cancer; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003955089,0.0001635175,0.002283535,0.0001935598,0.00007058162,0.000003721209,0.0001721887,0.00005809674,0.00005965679],"category_scores_gemma":[0.000471804,0.00007069937,0.0001789018,0.0007484143,0.0005142505,0.00003232582,0.00002119918,0.0002099196,7.255408e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002484006,"about_ca_system_score_gemma":0.000909419,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003625235,"about_ca_topic_score_gemma":0.00841355,"domain_scores_codex":[0.9954666,0.002552219,0.001013359,0.0002230961,0.0004387913,0.0003059574],"domain_scores_gemma":[0.9968157,0.001336219,0.001041594,0.0004944821,0.000219315,0.00009273046],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9179854,0.00127188,0.07370006,0.0002185178,0.001974058,0.000002300027,0.001592497,0.0003425062,0.0007016818,0.00002130517,0.00004034736,0.002149492],"study_design_scores_gemma":[0.8492323,0.03766044,0.1089502,0.0001391979,0.001306086,2.246202e-7,0.0001183717,0.0008743818,0.001628515,0.00001630994,0.000009834429,0.00006410818],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919505,0.0001562141,0.000002522987,0.001256332,0.0001042417,0.006144653,0.0001986473,0.000006230302,0.0001806998],"genre_scores_gemma":[0.9992719,0.00006521642,0.00001940548,0.0001049973,0.00005773617,0.0003541944,0.0000628098,0.00001132434,0.00005239073],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06875306,"threshold_uncertainty_score":0.5480295,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04686206875738232,"score_gpt":0.4188538237009971,"score_spread":0.3719917549436148,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}