{"id":"W2891646484","doi":"10.4049/jimmunol.1701805","title":"β1 Integrins Are Required To Mediate NK Cell Killing of <i>Cryptococcus neoformans</i>","year":2018,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Fungal Infections and Studies","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Cryptococcus neoformans; Biology; RAC1; Signal transduction; Cytolysis; Cell biology; Degranulation; Cryptococcosis; Integrin; Microbiology; Receptor; Cytotoxic T cell; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009209272,0.0001978047,0.0001221753,0.0001201106,0.0001446037,0.0002327609,0.000126878,0.0001736721,0.001667614],"category_scores_gemma":[0.0001280319,0.0001056517,0.0001590861,0.00005862904,0.0001356454,0.0001278363,0.0001164066,0.0002935071,0.0003886675],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003211661,"about_ca_system_score_gemma":0.0001572442,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001464077,"about_ca_topic_score_gemma":0.0009472246,"domain_scores_codex":[0.9998881,0.00001748167,0.00001035159,0.00001613282,0.00001886814,0.00004911659],"domain_scores_gemma":[0.9999086,0.00001607128,0.0000282008,0.00001021564,0.00001431477,0.00002261909],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009037097,0.0000171724,0.0007441795,0.00002107909,0.000002133485,0.0001651659,0.00001116677,0.00002839557,0.9980553,0.00008762596,0.00006248743,0.0007147971],"study_design_scores_gemma":[0.0000213517,0.0002182143,0.03935392,0.00001285561,0.0000173138,0.002082616,0.00008426201,0.00101048,0.9541466,0.0001042131,0.002944154,0.000004006202],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968302,0.0003925706,0.0006025277,0.00006739642,0.00001262796,0.00001012616,0.0001563999,0.00003561102,0.001892527],"genre_scores_gemma":[0.9983658,0.0001310616,0.0004033535,0.00002797609,0.000003039912,0.000007298861,0.0002291381,0.000004786573,0.0008275341],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001667614,"threshold_uncertainty_score":0.005578756,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01919149803280242,"score_gpt":0.273029348971819,"score_spread":0.2538378509390166,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}