{"id":"W2891826471","doi":"10.1016/j.brachy.2018.08.008","title":"Using a surgical prostate-specific antigen threshold of >0.2 ng/mL to define biochemical failure for intermediate- and high-risk prostate cancer patients treated with definitive radiation therapy in the ASCENDE-RT randomized control trial","year":2018,"lang":"en","type":"article","venue":"Brachytherapy","topic":"Prostate Cancer Diagnosis and Treatment","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"BC Cancer Agency","keywords":"Medicine; Urology; Prostate cancer; Prostate-specific antigen; Brachytherapy; Prostate; Radiation therapy; Nuclear medicine; Androgen suppression; Randomized controlled trial; Androgen deprivation therapy; Clinical endpoint; Internal medicine; Cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006001196,0.000347399,0.00100298,0.0001666137,0.00009262425,0.000046796,0.00008524121,0.0001216171,0.00002266593],"category_scores_gemma":[0.0000702523,0.0001922856,0.0001501958,0.0003480121,0.0003273392,0.00009587927,0.00001127626,0.0001511953,0.000001000147],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001440593,"about_ca_system_score_gemma":0.0001418361,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003968619,"about_ca_topic_score_gemma":0.00009157677,"domain_scores_codex":[0.9978747,0.0002394099,0.0006454,0.0005157896,0.0003309912,0.0003936505],"domain_scores_gemma":[0.9983237,0.0005795416,0.0003775762,0.0002503915,0.0003471721,0.0001216452],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8067166,0.001130589,0.1698488,0.00002510755,0.000493272,0.00001742597,0.003012192,0.000009348068,0.0007749482,0.00008439531,0.0002443432,0.01764305],"study_design_scores_gemma":[0.9145404,0.0144294,0.05638268,0.0002656665,0.0001966984,0.000008125273,0.00009588877,0.0002691722,0.01220207,0.0001342206,0.001206272,0.0002693996],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9844379,0.002611061,0.00005939013,0.0009154749,0.0001071675,0.01138479,0.0004425568,0.00003432434,0.000007310939],"genre_scores_gemma":[0.9890724,0.007107814,0.0003097701,0.0003560717,0.0002561679,0.002635525,0.0001930867,0.00006502356,0.000004125037],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1134661,"threshold_uncertainty_score":0.7841181,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02035631010197404,"score_gpt":0.2874713190631387,"score_spread":0.2671150089611646,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}