{"id":"W2891826471","doi":"10.1016/j.brachy.2018.08.008","title":"Using a surgical prostate-specific antigen threshold of &gt;0.2 ng/mL to define biochemical failure for intermediate- and high-risk prostate cancer patients treated with definitive radiation therapy in the ASCENDE-RT randomized control trial","year":2018,"lang":"en","type":"article","venue":"Brachytherapy","topic":"Prostate Cancer Diagnosis and Treatment","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"BC Cancer Agency","keywords":"Medicine; Urology; Prostate cancer; Prostate-specific antigen; Brachytherapy; Prostate; Radiation therapy; Nuclear medicine; Androgen suppression; Randomized controlled trial; Androgen deprivation therapy; Clinical endpoint; Internal medicine; Cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002122541,0.001354126,0.002054161,0.0003095368,0.0003403959,0.001118952,0.001088902,0.00156268,0.004198389],"category_scores_gemma":[0.003231584,0.0004767101,0.002820045,0.000276347,0.001269692,0.00111192,0.0004671708,0.002404763,0.0004158248],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005557709,"about_ca_system_score_gemma":0.0005992976,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001125132,"about_ca_topic_score_gemma":0.001994687,"domain_scores_codex":[0.9990202,0.0006212135,0.00006614375,0.0001615258,0.00004874136,0.00008227367],"domain_scores_gemma":[0.9987718,0.0004578994,0.0003266954,0.0001531814,0.00006064307,0.0002296915],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9826385,0.001272585,0.004091536,0.0004495977,0.002502196,0.00003173845,0.00004533845,0.0003464785,0.001277192,0.000245182,0.0007320023,0.006367569],"study_design_scores_gemma":[0.921048,0.04809802,0.02043031,0.00016981,0.006260698,0.0000945751,0.00007222999,0.001163125,0.0007270593,0.0007947065,0.001097793,0.00004368584],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9877274,0.006429679,0.0006319468,0.0007203877,0.0004927285,0.0008257734,0.0006529365,0.00008440055,0.002434787],"genre_scores_gemma":[0.9960341,0.0007128031,0.0005684015,0.0003902089,0.0003175251,0.0004657493,0.0006448869,0.000008094343,0.000858289],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004198389,"threshold_uncertainty_score":0.01404506,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02035631010197404,"score_gpt":0.2874713190631387,"score_spread":0.2671150089611646,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}