{"id":"W2892139286","doi":"10.1158/1538-7445.prca2017-a072","title":"Abstract A072: Serum sex steroids as prognostic biomarkers in patients receiving androgen-deprivation therapy for recurrent prostate cancer post-radiotherapy: A post hoc analysis of the PR.7 trial","year":2018,"lang":"en","type":"article","venue":"Cancer Research","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Cancer Society; University of Toronto; Université Laval","funders":"","keywords":"Medicine; Androgen deprivation therapy; Prostate cancer; Androstenediol; Testosterone (patch); Internal medicine; Androgen; Dihydrotestosterone; Oncology; Estrone; Cancer; Dehydroepiandrosterone; Endocrinology; Urology; Estrogen; Hormone","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004460638,0.001390841,0.002723285,0.0002491788,0.0003786235,0.001142675,0.0009624748,0.00087621,0.003577094],"category_scores_gemma":[0.003317674,0.0003698007,0.003380488,0.00043701,0.0008132585,0.0005963305,0.0004600381,0.002268061,0.0004583099],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00127469,"about_ca_system_score_gemma":0.002878633,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007865588,"about_ca_topic_score_gemma":0.01281919,"domain_scores_codex":[0.9975252,0.001623519,0.00009849392,0.000314451,0.0001863217,0.0002520442],"domain_scores_gemma":[0.9968113,0.001216637,0.0005672981,0.0003609999,0.0003677998,0.0006759814],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.9816568,0.0008233385,0.00648246,0.0002155467,0.003582989,0.00003155351,0.00003394521,0.0003039913,0.001282227,0.00004008453,0.0007309409,0.004816106],"study_design_scores_gemma":[0.6442905,0.2145332,0.1166214,0.00008640465,0.01593907,0.0001411265,0.0001526078,0.00343491,0.001793277,0.0002855822,0.002635579,0.00008637639],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935592,0.002004015,0.0002385266,0.000408004,0.0001395463,0.0007687776,0.001753511,0.00003674426,0.001091652],"genre_scores_gemma":[0.9937012,0.0004694124,0.0005976281,0.000316376,0.0002365137,0.0007274219,0.002239879,0.00001902954,0.00169238],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007865588,"threshold_uncertainty_score":0.02359039,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05896490622204424,"score_gpt":0.4162091243379175,"score_spread":0.3572442181158733,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}