{"id":"W2892303659","doi":"10.1093/toxsci/kfy230","title":"Genomic Profiling of BDE-47 Effects on Human Placental Cytotrophoblasts","year":2018,"lang":"en","type":"article","venue":"Toxicological Sciences","topic":"Birth, Development, and Health","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; McMaster University; National Institute of Environmental Health Sciences; Department of Toxic Substances Control; U.S. Environmental Protection Agency","keywords":"Transcriptome; Placenta; Biology; Polybrominated diphenyl ethers; Placentation; DNA methylation; Cell biology; Fetus; Andrology; Endocrinology; Pregnancy; Gene expression; Genetics; Medicine; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005958496,0.0001102574,0.0002576551,0.00008933045,0.0003408274,0.00001449543,0.0001787007,0.0001035192,0.0002839705],"category_scores_gemma":[0.0001306303,0.00006724904,0.00004512697,0.0002772303,0.0007697921,0.00003439609,0.00006869998,0.0001425413,0.0001232957],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001017641,"about_ca_system_score_gemma":0.0001734082,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000107927,"about_ca_topic_score_gemma":0.0000145898,"domain_scores_codex":[0.9986445,0.00006213603,0.0002265155,0.0003268374,0.0003602748,0.0003797685],"domain_scores_gemma":[0.9994738,0.0001085021,0.00009604398,0.0001017521,0.00004036288,0.0001795704],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001766982,0.0003233605,0.1072286,0.00008957757,0.00001003761,0.00001866252,0.0002218121,0.000001606085,0.8498771,0.03830549,0.000340342,0.003406785],"study_design_scores_gemma":[0.0007470353,0.009596601,0.6641374,0.00009422235,0.000009258935,0.00001479356,0.00009035735,0.00007808246,0.3212033,0.003823927,0.000093634,0.0001113235],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9724109,0.00003534431,0.00001581067,0.0003962817,0.0002029758,0.0003957349,0.000001354101,0.00004704854,0.02649458],"genre_scores_gemma":[0.9956828,0.0001426698,0.002522234,0.001325944,0.0002704202,0.00001071307,0.000001618035,0.000004003618,0.00003957432],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5569089,"threshold_uncertainty_score":0.3109278,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07007718347568404,"score_gpt":0.3662498359741413,"score_spread":0.2961726524984573,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}