{"id":"W2892303659","doi":"10.1093/toxsci/kfy230","title":"Genomic Profiling of BDE-47 Effects on Human Placental Cytotrophoblasts","year":2018,"lang":"en","type":"article","venue":"Toxicological Sciences","topic":"Birth, Development, and Health","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; McMaster University; National Institute of Environmental Health Sciences; Department of Toxic Substances Control; U.S. Environmental Protection Agency","keywords":"Transcriptome; Placenta; Biology; Polybrominated diphenyl ethers; Placentation; DNA methylation; Cell biology; Fetus; Andrology; Endocrinology; Pregnancy; Gene expression; Genetics; Medicine; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001476573,0.0002089271,0.0003112828,0.0005740019,0.0002339446,0.0004134953,0.00009992336,0.0002425146,0.001238306],"category_scores_gemma":[0.0002828778,0.0001580655,0.0003566589,0.0006690813,0.0001520143,0.00009464149,0.000253188,0.0003416945,0.000647476],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001985341,"about_ca_system_score_gemma":0.0002725225,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001737814,"about_ca_topic_score_gemma":0.003006415,"domain_scores_codex":[0.9998174,0.00001716109,0.000009686112,0.00006646805,0.00006267895,0.00002663012],"domain_scores_gemma":[0.9998866,0.00002525085,0.00002225546,0.00001111535,0.00004313462,0.00001159739],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002455934,0.00001831834,0.007072617,0.0001421392,0.00003285201,0.0001385664,0.00014721,0.0001640415,0.985701,0.00005730497,0.0002060043,0.006074302],"study_design_scores_gemma":[0.00003219931,0.0009079285,0.3969756,0.00008635659,0.0003526618,0.001192921,0.0009683933,0.001643953,0.574549,0.0003506633,0.02289539,0.00004507837],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9508359,0.009337348,0.009588677,0.0002308012,0.00005901452,0.0001488864,0.02557579,0.0001705292,0.004053028],"genre_scores_gemma":[0.9485453,0.008318073,0.009766595,0.0003645643,0.0000354923,0.0003733475,0.02558864,0.00007307795,0.00693502],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001737814,"threshold_uncertainty_score":0.004142582,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07007718347568404,"score_gpt":0.3662498359741413,"score_spread":0.2961726524984573,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}