{"id":"W2892342442","doi":"10.3324/haematol.2018.203224","title":"<i>JUNB</i>, <i>DUSP2</i>, <i>SGK1</i>, <i>SOCS1</i> and <i>CREBBP</i> are frequently mutated in T-cell/histiocyte-rich large B-cell lymphoma","year":2018,"lang":"en","type":"article","venue":"Haematologica","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":64,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"Deutsche Forschungsgemeinschaft","keywords":"Lymphoma; Somatic hypermutation; JUNB; Pathology; Histiocyte; Cancer research; BCL6; B cell; Germinal center; Biology; Medicine; Immunology; Genetics; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003959976,0.0007279982,0.001386023,0.0002643251,0.0003552924,0.0001000623,0.0002866305,0.0004776471,0.0002709933],"category_scores_gemma":[0.0001794368,0.0005783011,0.0002218088,0.0008029763,0.0004416687,0.0001910241,0.0002512414,0.0002383175,0.0007477278],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003425194,"about_ca_system_score_gemma":0.0002263504,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002714808,"about_ca_topic_score_gemma":0.000235433,"domain_scores_codex":[0.9958946,0.0001929416,0.0009198112,0.001225318,0.00055746,0.001209858],"domain_scores_gemma":[0.9975686,0.0003416149,0.0004336194,0.000874044,0.0002545119,0.0005276243],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001992846,0.0272452,0.8268629,0.001423202,0.0003562529,0.01782662,0.001857656,0.000002782192,0.01673572,0.002474335,0.0978616,0.005360901],"study_design_scores_gemma":[0.09014786,0.003617528,0.178363,0.001311089,0.001089404,0.005201539,0.001914693,0.0003400008,0.5170938,0.001214586,0.1970941,0.002612349],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9486403,0.006133554,0.00003286041,0.001579442,0.0003165356,0.001147605,0.0001058678,0.000339842,0.04170398],"genre_scores_gemma":[0.9898757,0.001508118,0.001315215,0.005689355,0.0001675169,0.0002741625,0.0001195911,0.00008000994,0.0009703671],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6484998,"threshold_uncertainty_score":0.9996669,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01232129189129027,"score_gpt":0.2443443133510099,"score_spread":0.2320230214597196,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}