{"id":"W2892382386","doi":"10.21037/jtd.2018.09.80","title":"The need to move away from fecal transplant towards targeted, refined microbiome therapy","year":2018,"lang":"en","type":"letter","venue":"Journal of Thoracic Disease","topic":"Clostridium difficile and Clostridium perfringens research","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Microbiome; Fecal bacteriotherapy; Medicine; Feces; Intensive care medicine; Bioinformatics; Ecology; Microbiology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003279496,0.0005872532,0.001068122,0.0005473507,0.001164126,0.002725527,0.0009289139,0.01539536,0.007488303],"category_scores_gemma":[0.01623395,0.0002318796,0.0008624064,0.0003066293,0.00241517,0.005725977,0.00150325,0.02705099,0.006035258],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001867913,"about_ca_system_score_gemma":0.001265974,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004431986,"about_ca_topic_score_gemma":0.0009611002,"domain_scores_codex":[0.997617,0.0007476067,0.0002962286,0.000315859,0.0008447763,0.0001786084],"domain_scores_gemma":[0.9885659,0.00759683,0.0005971869,0.000352291,0.001645067,0.001242773],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009277843,0.00007869994,0.0005123128,0.0005928362,0.0000260056,0.002908963,0.0001885607,0.0001465705,0.001084204,0.007275148,0.8803997,0.1066942],"study_design_scores_gemma":[0.00005302392,0.0001460058,0.000432917,0.0006224055,0.00002210749,0.005621909,0.0002631011,0.0002426095,0.0002824432,0.01455844,0.9777197,0.00003538432],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0004488086,0.0268021,0.0007909532,0.9350137,0.03484395,0.00001118706,0.00002767255,0.00006398802,0.001997649],"genre_scores_gemma":[0.005823446,0.03241544,0.001776809,0.7946576,0.159967,0.00002914307,0.00004316112,0.00004641627,0.005241012],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.01539536,"threshold_uncertainty_score":0.02505088,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02947624064056189,"score_gpt":0.3347177491620699,"score_spread":0.3052415085215081,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}