{"id":"W2893124275","doi":"10.1021/acs.biochem.8b00900","title":"Instantaneous Iodine-Assisted DNAzyme Cleavage of Phosphorothioate RNA","year":2018,"lang":"en","type":"article","venue":"Biochemistry","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"Social Sciences and Humanities Research Council of Canada; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Deoxyribozyme; Cleavage (geology); Chemistry; Cleave; Metal; RNA; Metal ions in aqueous solution; Yield (engineering); Photochemistry; DNA; Biochemistry; Materials science; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003221993,0.0004423051,0.0002766386,0.0001791291,0.00007569665,0.0003142621,0.0004327218,0.0004866572,0.0008015079],"category_scores_gemma":[0.0004598875,0.0002281683,0.0003395867,0.0001729889,0.000254073,0.0002169044,0.0002707294,0.0005307938,0.0004106672],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000349401,"about_ca_system_score_gemma":0.0001724252,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003484906,"about_ca_topic_score_gemma":0.0006396231,"domain_scores_codex":[0.9997448,0.00003570095,0.00001697841,0.00008652687,0.00006384358,0.00005213088],"domain_scores_gemma":[0.9998028,0.00005838697,0.00004580469,0.00002248079,0.00003692503,0.00003365468],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001875539,0.000003578638,0.00006366712,0.00002254379,0.000003202271,0.00001614034,0.00001129342,0.00004822181,0.9987602,0.00003343545,0.000008038578,0.001010901],"study_design_scores_gemma":[0.000001970292,0.00003445732,0.0002247495,0.000001030662,0.000002386831,0.00003583548,0.000002831012,0.0002221966,0.9992567,0.000005314032,0.0002108139,0.000001716303],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9673193,0.001109822,0.02910124,0.00006363307,0.00002218932,0.00004265609,0.0002006139,0.0002026011,0.00193811],"genre_scores_gemma":[0.9740959,0.0004113321,0.02213066,0.00003280534,0.000005909786,0.0000264493,0.0003082578,0.0000537084,0.002934974],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008015079,"threshold_uncertainty_score":0.002681315,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008670416987656134,"score_gpt":0.259817851697308,"score_spread":0.2511474347096518,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}