{"id":"W2893131042","doi":"10.1111/aji.13054","title":"Decidual leucocytes infiltrating human spiral arterioles are rich source of matrix metalloproteinases and degrade extracellular matrix in vitro and in situ","year":2018,"lang":"en","type":"article","venue":"American Journal of Reproductive Immunology","topic":"Preterm Birth and Chorioamnionitis","field":"Medicine","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"Biotechnology and Biological Sciences Research Council; Medical Research Council","keywords":"Matrix metalloproteinase; Decidua; MMP9; MMP2; Extracellular matrix; Cell biology; Immunology; Immunofluorescence; Spiral artery; Biology; Zymography; Trophoblast; Andrology; Chemistry; Placenta; Fetus; Medicine; Antibody; Biochemistry; Downregulation and upregulation; Pregnancy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002185507,0.0002001107,0.0001619644,0.0002143718,0.0001562195,0.0003171043,0.00008928103,0.00015467,0.002138942],"category_scores_gemma":[0.0002175484,0.0001430462,0.0001934168,0.0001849451,0.0001680567,0.0001398125,0.0001766729,0.0002581048,0.0007336662],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001141582,"about_ca_system_score_gemma":0.0001657168,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005365238,"about_ca_topic_score_gemma":0.0007050302,"domain_scores_codex":[0.9997895,0.00004384538,0.00002080542,0.00004923255,0.00005271515,0.00004391807],"domain_scores_gemma":[0.9999033,0.00002179033,0.00002349391,0.0000179079,0.00001694112,0.00001655711],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001350752,0.00002342224,0.002007398,0.00009617856,0.000006572167,0.0002123393,0.0001123537,0.00001975828,0.9942069,0.00007801698,0.00005968868,0.003042286],"study_design_scores_gemma":[0.00006190126,0.0008210676,0.05341256,0.00006351889,0.00008306355,0.003556749,0.0003924052,0.0008125547,0.9245526,0.0001615799,0.01607009,0.00001181699],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9800306,0.008659567,0.006576881,0.0001288535,0.00004617863,0.00008954222,0.0005784763,0.0000940369,0.003795854],"genre_scores_gemma":[0.9894497,0.002042077,0.004108306,0.00006526528,0.00002688452,0.00007498146,0.0007172445,0.00001083388,0.003504705],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002138942,"threshold_uncertainty_score":0.007155478,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01079757906653333,"score_gpt":0.2783170042557671,"score_spread":0.2675194251892338,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}