{"id":"W2893374752","doi":"10.1016/j.cjca.2018.07.306","title":"ULTRASOUND-TARGETED MICROBUBBLE DESTRUCTION-MEDIATED MIRNA-495 DELIVERY IMPROVES CARDIAC FUNCTION POST MYOCARDIAL ISCHEMIA/REPERFUSION INJURY THROUGH INHIBITING APOPTOSIS","year":2018,"lang":"en","type":"article","venue":"Canadian Journal of Cardiology","topic":"Ultrasound and Hyperthermia Applications","field":"Engineering","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Toronto Public Health","funders":"","keywords":"Medicine; Apoptosis; Blot; In vivo; Annexin; Reperfusion injury; Cardiac function curve; microRNA; Ischemia; Downregulation and upregulation; Myocardial infarction; Transfection; Molecular biology; Andrology; Internal medicine; Cell culture; Immunology; Flow cytometry; Biology; Biochemistry; Heart failure; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001564523,0.0002940354,0.0003589829,0.0001956096,0.0001917995,0.0003021187,0.0001920611,0.000439391,0.001699931],"category_scores_gemma":[0.0001707233,0.0001564562,0.0003348106,0.0000843616,0.0002832024,0.0003516402,0.0002017332,0.0005998625,0.0003278517],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002649063,"about_ca_system_score_gemma":0.00027106,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004842325,"about_ca_topic_score_gemma":0.0007016078,"domain_scores_codex":[0.9998574,0.00001473178,0.00000933182,0.00003609086,0.00004299143,0.00003940371],"domain_scores_gemma":[0.9999615,0.000007240269,0.00001218932,0.000003399652,0.000006138856,0.000009680479],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003752099,0.00009267269,0.0001282898,0.00006866042,0.00001195205,0.00005057514,0.00002093393,0.0001214712,0.9910229,0.0002437417,0.0001677751,0.007695845],"study_design_scores_gemma":[0.00004425047,0.0006319752,0.001092112,0.000005170536,0.00004444396,0.0001239279,0.0000138472,0.001437026,0.9947248,0.00007518486,0.001799624,0.000007591098],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9745462,0.004491683,0.01619904,0.0002428366,0.0002476733,0.0001016798,0.0001300512,0.0003750288,0.003665739],"genre_scores_gemma":[0.9936888,0.0009267325,0.002787064,0.0001231269,0.00002383643,0.00004760196,0.00008249273,0.00002056114,0.00229999],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001699931,"threshold_uncertainty_score":0.00568682,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005522996597888828,"score_gpt":0.1855914385499979,"score_spread":0.1800684419521091,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}