{"id":"W2893664438","doi":"10.1016/j.ajpath.2018.08.013","title":"Enteroviral Infection Leads to Transactive Response DNA-Binding Protein 43 Pathology in Vivo","year":2018,"lang":"en","type":"article","venue":"American Journal Of Pathology","topic":"Amyotrophic Lateral Sclerosis Research","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; University of British Columbia; Fondation Brain Canada; ALS Society of Canada","keywords":"Astrogliosis; Pathology; Biology; Gliosis; Cerebral cortex; Microglia; Amyotrophic lateral sclerosis; Coxsackievirus; Neuroinflammation; Medicine; Virology; Immunology; Virus; Inflammation; Enterovirus; Central nervous system; Neuroscience; Disease","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005150643,0.0007709402,0.0004085684,0.0006498038,0.0005739675,0.001035188,0.0003334142,0.0008725259,0.00315128],"category_scores_gemma":[0.0003172631,0.0004601109,0.0004950272,0.0002597178,0.0005699274,0.0004857852,0.0004531013,0.002194369,0.001511707],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005532855,"about_ca_system_score_gemma":0.0004470678,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001063831,"about_ca_topic_score_gemma":0.001069302,"domain_scores_codex":[0.9991756,0.0001696895,0.00004566216,0.0001698005,0.000206113,0.0002332138],"domain_scores_gemma":[0.9995041,0.0001089372,0.00009735666,0.0000782429,0.00004431982,0.0001670113],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002102957,0.00008942879,0.0001243026,0.00001844581,0.00001069318,0.0001114512,0.0000341561,0.00005353095,0.9985918,0.0002214948,0.0000979774,0.0004362944],"study_design_scores_gemma":[0.00004670294,0.0004275528,0.003261711,0.000009116786,0.00002607892,0.0008555297,0.0001075794,0.001661507,0.9918445,0.0002380972,0.001510533,0.00001104694],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9858099,0.001388356,0.006030227,0.0003636143,0.0002415866,0.00004009511,0.0004823553,0.0003119475,0.005331911],"genre_scores_gemma":[0.989377,0.0004609069,0.002285783,0.00009659382,0.00001924741,0.00003224442,0.0005286483,0.000101853,0.007097674],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00315128,"threshold_uncertainty_score":0.01054204,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01978207354163856,"score_gpt":0.3245092391043086,"score_spread":0.30472716556267,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}