{"id":"W2893786954","doi":"10.1161/circ.132.suppl_3.18789","title":"Abstract 18789: BRCA2 is a Novel Regulator of Endothelial Cell Function and Apoptosis Following Hyperglycemia","year":2015,"lang":"en","type":"article","venue":"Circulation","topic":"Cardiovascular Health and Risk Factors","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital","funders":"","keywords":"Medicine; Apoptosis; Endothelial dysfunction; Gene silencing; Endocrinology; Cancer research; Internal medicine; DNA damage; TUNEL assay; Endothelial stem cell; Biology; In vitro; DNA; Gene; Immunohistochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000268337,0.0001024118,0.0002572383,0.0001047086,0.00004534071,0.000008927071,0.00002095577,0.0001331828,0.00001439621],"category_scores_gemma":[0.00007041715,0.00009398853,0.0001964177,0.000132782,0.0000230585,0.000103804,0.00001046225,0.0000960275,0.00001085192],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000879492,"about_ca_system_score_gemma":0.0001447479,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002107544,"about_ca_topic_score_gemma":0.000002119993,"domain_scores_codex":[0.99904,0.00001285692,0.0002515033,0.00020336,0.0003451815,0.0001471148],"domain_scores_gemma":[0.9993588,0.00002380918,0.00009787572,0.0002245865,0.00009651542,0.0001984102],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0006445853,0.0001828415,0.6448746,0.0004465211,0.0002553923,0.000002530856,0.001257519,0.0002382343,0.3357179,0.00007535291,0.0005470844,0.01575749],"study_design_scores_gemma":[0.00452732,0.00007193829,0.97537,0.00007288654,0.0003055197,0.00001523809,0.0002173313,0.0004959288,0.01614915,0.00008316604,0.002569445,0.0001221075],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963262,0.0005874746,0.001469279,0.0001074373,0.0004422162,0.0002844978,0.00001048438,0.0000357585,0.000736672],"genre_scores_gemma":[0.999313,0.00002015001,0.0002601855,0.0001241715,0.0001915537,0.000005297809,0.000033318,0.00001881031,0.00003352964],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3304954,"threshold_uncertainty_score":0.3832741,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02814949910393558,"score_gpt":0.2593938752483297,"score_spread":0.2312443761443941,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}