{"id":"W2893786954","doi":"10.1161/circ.132.suppl_3.18789","title":"Abstract 18789: BRCA2 is a Novel Regulator of Endothelial Cell Function and Apoptosis Following Hyperglycemia","year":2015,"lang":"en","type":"article","venue":"Circulation","topic":"Cardiovascular Health and Risk Factors","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital","funders":"","keywords":"Medicine; Apoptosis; Endothelial dysfunction; Gene silencing; Endocrinology; Cancer research; Internal medicine; DNA damage; TUNEL assay; Endothelial stem cell; Biology; In vitro; DNA; Gene; Immunohistochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001905784,0.0003438362,0.0004109167,0.0002416271,0.000212638,0.0004471428,0.0003170835,0.0004168637,0.0042349],"category_scores_gemma":[0.0001395864,0.0001595291,0.0003524457,0.0002724038,0.0001774298,0.0001768426,0.0002127435,0.0007632694,0.001433665],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003008638,"about_ca_system_score_gemma":0.0002109311,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003029896,"about_ca_topic_score_gemma":0.0002395651,"domain_scores_codex":[0.9998575,0.00001692432,0.00001353178,0.00004221003,0.00004319054,0.00002655986],"domain_scores_gemma":[0.9998984,0.00001263432,0.00004010411,0.000008698951,0.00001472388,0.00002542561],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009371097,0.0001177641,0.002410916,0.0003987683,0.00006198505,0.001292898,0.00003583525,0.00009983204,0.9803623,0.0002639627,0.002848494,0.01117004],"study_design_scores_gemma":[0.0002939389,0.001130612,0.1146584,0.0001085953,0.0003261121,0.01238641,0.0001208025,0.00208108,0.8265365,0.0005360051,0.04178798,0.00003352585],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.942783,0.0293276,0.008585401,0.002435223,0.001081289,0.000153622,0.0076435,0.0007577901,0.007232494],"genre_scores_gemma":[0.9636588,0.008786756,0.002920201,0.0009354657,0.0003737875,0.0001566562,0.009499575,0.00008175999,0.01358694],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0042349,"threshold_uncertainty_score":0.01416719,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02814949910393558,"score_gpt":0.2593938752483297,"score_spread":0.2312443761443941,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}