{"id":"W2893841296","doi":"10.1039/c8ob01868e","title":"A novel route towards cycle-tail peptides using oxime resin: teaching an old dog a new trick","year":2018,"lang":"en","type":"article","venue":"Organic & Biomolecular Chemistry","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Fonds de recherche du Québec – Nature et technologies; Natural Sciences and Engineering Research Council of Canada","keywords":"Oxime; Chemistry; Side chain; Cleavage (geology); Combinatorial chemistry; Stereochemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002921379,0.0004517638,0.0003920845,0.00004437892,0.0002603273,0.0001510615,0.0006408317,0.0004490518,0.0004681506],"category_scores_gemma":[0.0003383114,0.0004466478,0.000345555,0.0003308666,0.0001893063,0.00001676437,0.000339835,0.0002480552,0.00003776372],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001067811,"about_ca_system_score_gemma":0.0002949477,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004873647,"about_ca_topic_score_gemma":0.00001721223,"domain_scores_codex":[0.9975185,0.00005149,0.0004498393,0.001015345,0.0003591746,0.0006056923],"domain_scores_gemma":[0.9981772,0.000009302849,0.0002093723,0.001029748,0.000127314,0.0004470887],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000432096,0.0001941892,0.0001633863,0.00003273096,0.0001897535,0.00001337978,0.00005088727,7.795533e-7,0.9965214,0.000004887174,0.0004658757,0.002319518],"study_design_scores_gemma":[0.0007194647,0.00008451583,0.00008840809,0.0000532079,0.000189001,0.0001211546,0.00008936301,0.0004569982,0.9890957,0.00004637825,0.008461664,0.0005941648],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8945174,0.0004475854,0.1021912,0.0002452184,0.00005582611,0.0001030672,0.00003193331,0.00006712167,0.002340704],"genre_scores_gemma":[0.986373,0.00002993177,0.008688319,0.0004468945,0.001418762,0.000004239944,0.000198685,0.0001025286,0.002737617],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09350289,"threshold_uncertainty_score":0.9997985,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01261368451599935,"score_gpt":0.2707644722447409,"score_spread":0.2581507877287416,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}