{"id":"W2893919806","doi":"10.1158/0008-5472.can-18-0362","title":"Sex Differences in Cancer Driver Genes and Biomarkers","year":2018,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":189,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Ontario Institute for Cancer Research","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Terry Fox Research Institute; Ontario Institute for Cancer Research","keywords":"Cancer; Microsatellite instability; Somatic cell; Gene; Mutation; Germline mutation; Biology; Oncology; BAP1; Medicine; Internal medicine; Genetics; Bioinformatics; Microsatellite; Allele","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002558878,0.00009216881,0.0001087332,0.00009238596,0.0001043417,0.00004326653,0.0001716099,0.00009236347,0.0001398937],"category_scores_gemma":[0.00005329395,0.00008473077,0.00002038507,0.0001710312,0.0004570489,0.000002802815,0.0002123008,0.00009643681,0.000006139355],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005705114,"about_ca_system_score_gemma":0.0002573466,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003027685,"about_ca_topic_score_gemma":0.007122147,"domain_scores_codex":[0.9989723,0.00005996266,0.0001065262,0.0003563193,0.0001564028,0.0003485041],"domain_scores_gemma":[0.9995054,0.00003585541,0.00001978186,0.0002003501,0.0001395627,0.00009905211],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001454542,0.0000338543,0.2921707,0.00002815059,0.00005756535,0.000005004343,0.0002301747,0.000003367013,0.6502979,0.00008386729,0.008561554,0.0483823],"study_design_scores_gemma":[0.001262052,0.0005706854,0.1467702,0.00008848981,0.00001156411,0.000003828309,0.0004226554,0.0001574644,0.6646961,0.0004286982,0.185181,0.0004072273],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9866883,0.01153138,0.00001722873,0.0004762638,0.0001737201,0.0001601494,0.00004598089,0.00000341331,0.0009036346],"genre_scores_gemma":[0.9773965,0.02062695,0.00004826518,0.0001433753,0.0006211829,0.0001345342,0.000007215778,0.00001526541,0.00100669],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1766195,"threshold_uncertainty_score":0.4576975,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05859867445819356,"score_gpt":0.3803946211040359,"score_spread":0.3217959466458423,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}