{"id":"W2893945844","doi":"10.1007/s11010-018-3450-5","title":"Leptin-induced cardiomyocyte hypertrophy is associated with enhanced mitochondrial fission","year":2018,"lang":"en","type":"article","venue":"Molecular and Cellular Biochemistry","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"Mitochondrial fission; mitochondrial fusion; Leptin; Mitochondrion; Internal medicine; Muscle hypertrophy; Endocrinology; Calcineurin; Biology; Mitochondrial biogenesis; DNM1L; MFN2; Mitochondrial DNA; Cell biology; Chemistry; Medicine; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002522396,0.0004603022,0.0004613938,0.0005242989,0.0002846702,0.0003606615,0.0002046308,0.0004566627,0.001351298],"category_scores_gemma":[0.0001820407,0.0003628173,0.0004766738,0.0002890222,0.0004121761,0.0005426701,0.0004663273,0.0009039139,0.0003411163],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003433257,"about_ca_system_score_gemma":0.0001799671,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003816267,"about_ca_topic_score_gemma":0.00062491,"domain_scores_codex":[0.9997411,0.00003859067,0.00003100333,0.00004869951,0.0000842856,0.00005631212],"domain_scores_gemma":[0.9996939,0.00002610181,0.0001080328,0.00003490483,0.00002768979,0.0001093529],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006243079,0.00001549377,0.0003039288,0.00002923054,0.00001190681,0.0002414288,0.00001215572,0.00001225892,0.9981962,0.00006170809,0.00001699183,0.000474352],"study_design_scores_gemma":[0.00009133876,0.0005039716,0.0539305,0.0000191585,0.00005852742,0.002200509,0.000152437,0.0004511373,0.9410185,0.0002424821,0.001318024,0.00001341169],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9907902,0.004004624,0.00327502,0.0002661354,0.0001065433,0.00002526145,0.0003964672,0.00008262144,0.001053065],"genre_scores_gemma":[0.9939005,0.001262386,0.002242695,0.00009211997,0.00003480099,0.00004566645,0.000404618,0.0000286305,0.001988501],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001351298,"threshold_uncertainty_score":0.004520535,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006702596181140077,"score_gpt":0.2112848935464704,"score_spread":0.2045822973653303,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}