{"id":"W2894088295","doi":"10.1016/j.omtn.2018.09.018","title":"Genetic Strategies for HIV Treatment and Prevention","year":2018,"lang":"en","type":"review","venue":"Molecular Therapy — Nucleic Acids","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Foundation for AIDS Research","keywords":"Biology; Secretion; Cytotoxic T cell; Haematopoiesis; Virology; Genetic enhancement; Cell biology; Viral replication; Virus; Immunology; Gene; Stem cell; In vitro; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000342125,0.0005992939,0.0006989627,0.001519843,0.0003265313,0.0007714464,0.0006976776,0.0009658999,0.005243463],"category_scores_gemma":[0.0003562679,0.0001863675,0.0004184577,0.000894279,0.0005324426,0.0009221213,0.0005970476,0.00175705,0.002528405],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006201309,"about_ca_system_score_gemma":0.0007306506,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005348516,"about_ca_topic_score_gemma":0.0008217377,"domain_scores_codex":[0.9998195,0.00003337007,0.00001541414,0.00002680977,0.00008374797,0.00002128442],"domain_scores_gemma":[0.9998957,0.00004334954,0.00001586623,0.000007245623,0.00002591241,0.00001201984],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005869228,0.0001432295,0.0001758321,0.009114158,0.00006461947,0.0003702211,0.0001037293,0.0004205365,0.01170505,0.02511102,0.03103558,0.9216974],"study_design_scores_gemma":[0.000008547085,0.00006746941,0.0002069638,0.001061433,0.00003339111,0.001124725,0.00003177848,0.00007661678,0.002804345,0.004184146,0.9903885,0.00001217197],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004421319,0.9906259,0.001179513,0.0006155876,0.0004228498,0.00001973373,0.00003587193,0.00003283521,0.006625614],"genre_scores_gemma":[0.003292344,0.991345,0.001165803,0.0004154917,0.0001956428,0.00002864507,0.00006123408,0.000007223589,0.003488629],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005243463,"threshold_uncertainty_score":0.01754111,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04358200410814942,"score_gpt":0.3578649236917202,"score_spread":0.3142829195835708,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}