{"id":"W2894088295","doi":"10.1016/j.omtn.2018.09.018","title":"Genetic Strategies for HIV Treatment and Prevention","year":2018,"lang":"en","type":"review","venue":"Molecular Therapy — Nucleic Acids","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Foundation for AIDS Research","keywords":"Biology; Secretion; Cytotoxic T cell; Haematopoiesis; Virology; Genetic enhancement; Cell biology; Viral replication; Virus; Immunology; Gene; Stem cell; In vitro; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002501345,0.0006885256,0.000886499,0.0001428945,0.0001617305,0.0001519021,0.0004390221,0.0005709731,0.00006088326],"category_scores_gemma":[0.0000132565,0.0005659228,0.0007039275,0.0001419882,0.0002256019,0.000006032294,0.00009782797,0.0001226394,0.00004168692],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007573372,"about_ca_system_score_gemma":0.0005701043,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004445269,"about_ca_topic_score_gemma":0.0000180957,"domain_scores_codex":[0.9974721,0.0003508409,0.0004643546,0.0009790465,0.0001918476,0.0005417889],"domain_scores_gemma":[0.9985388,0.00002108699,0.0002128281,0.0009583799,0.0001132403,0.0001556952],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005637911,0.0001297944,0.000001884259,0.0008302843,0.001068504,0.000008390231,0.00004060775,0.000002781446,0.01313304,0.00003864851,0.0005229697,0.9836593],"study_design_scores_gemma":[0.001407076,0.01047867,0.000001706783,0.000376636,0.0002374948,0.00003937745,0.00002094205,0.000007906468,0.006380005,0.0004911908,0.9799839,0.0005750707],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01395081,0.9795192,0.003743638,0.00002672155,0.0001020778,0.002362392,0.0001006142,0.00003299683,0.0001615417],"genre_scores_gemma":[0.0003531952,0.9946154,0.001743687,0.00009533907,0.0004540595,0.0009054012,0.0005624556,0.0002279977,0.001042415],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9830843,"threshold_uncertainty_score":0.9996792,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04358200410814942,"score_gpt":0.3578649236917202,"score_spread":0.3142829195835708,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}