{"id":"W2894461003","doi":"10.3389/fcimb.2018.00331","title":"Protegrin 1 Enhances Innate Cellular Defense via the Insulin-Like Growth Factor 1 Receptor Pathway","year":2018,"lang":"en","type":"article","venue":"Frontiers in Cellular and Infection Microbiology","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Foshan University; Ministry of Agriculture, Food and Rural Affairs; Functional Polymer Materials and Fine Chemicals Center, Foshan Center of Chinese Academy of Sciences; Natural Sciences and Engineering Research Council of Canada; Ontario Ministry of Agriculture, Food and Rural Affairs","keywords":"Cathelicidin; Immune system; Antimicrobial peptides; Innate immune system; Biology; Receptor; Growth factor; Immunology; Cell biology; Inflammation; Microbiology; Antimicrobial; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001064737,0.0003641562,0.0002171888,0.0001977746,0.00008534325,0.0002477104,0.0001052862,0.0002266205,0.0008800765],"category_scores_gemma":[0.0001055244,0.00006886859,0.000223757,0.00009465874,0.0001971728,0.0001749594,0.000192286,0.0006126451,0.0001982413],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002177057,"about_ca_system_score_gemma":0.0001452636,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001789725,"about_ca_topic_score_gemma":0.0003513845,"domain_scores_codex":[0.9998773,0.00003593243,0.000005194351,0.00001729071,0.00001842599,0.00004570116],"domain_scores_gemma":[0.9999429,0.00001042349,0.00001963566,0.000004343574,0.000005497939,0.00001718728],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003967667,0.00005621832,0.0002489467,0.0001050108,0.000004802529,0.0001183734,0.00001596292,0.00006373373,0.9946884,0.00009022394,0.0000692161,0.004142345],"study_design_scores_gemma":[0.000131202,0.003544264,0.03765408,0.00004880151,0.00006040665,0.0008360596,0.0001713433,0.001509664,0.9469683,0.0004000445,0.008658775,0.0000170568],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9886461,0.00660755,0.001388922,0.0004731939,0.00006683149,0.00002986553,0.0001539286,0.00007244313,0.002561179],"genre_scores_gemma":[0.9950236,0.002148473,0.00134365,0.0001271293,0.00002498655,0.00002232989,0.000117992,0.000005899016,0.001185903],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008800765,"threshold_uncertainty_score":0.002944112,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007328795698467679,"score_gpt":0.1932610780601961,"score_spread":0.1859322823617284,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}