{"id":"W2894768123","doi":"10.1007/s10741-018-9743-7","title":"Intercalated discs: cellular adhesion and signaling in heart health and diseases","year":2018,"lang":"en","type":"review","venue":"Heart Failure Reviews","topic":"Cardiovascular Effects of Exercise","field":"Medicine","cited_by":76,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia Hospital; St. Paul's Hospital; University of British Columbia","funders":"Institute of Circulatory and Respiratory Health; Heart and Stroke Foundation of Canada","keywords":"Adherens junction; Intercalated disc; Cell biology; Plakoglobin; Medicine; Cardiomyopathy; Signal transduction; Heart failure; Wnt signaling pathway; Actin cytoskeleton; Desmoplakin; Actin; Cadherin; Biology; Catenin; Internal medicine; Cytoskeleton; Gap junction; Cell; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00187632,0.0007419771,0.006891254,0.0004073828,0.00009876255,0.00007335345,0.0001024299,0.0003536898,0.0000524858],"category_scores_gemma":[0.0005960752,0.0005235961,0.001327157,0.000513117,0.0001656771,0.00011651,0.0002118904,0.0006964245,0.0001864885],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001879432,"about_ca_system_score_gemma":0.0003451053,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005406624,"about_ca_topic_score_gemma":0.00002157867,"domain_scores_codex":[0.995296,0.001401367,0.00140211,0.001023845,0.0003379671,0.0005387099],"domain_scores_gemma":[0.997681,0.0002412141,0.0003031292,0.0009462422,0.00005141903,0.0007770176],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002791546,0.0001039029,0.0002783094,0.1887648,0.0001335664,0.00007243099,0.00008636726,1.850315e-8,0.00001384904,0.00000335002,0.03537834,0.7751372],"study_design_scores_gemma":[0.0004199003,0.0002705156,0.00002683105,0.1825125,0.001007199,0.0004739242,0.00001064226,0.000002668252,0.000001875814,0.000004385882,0.814936,0.0003335931],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001352831,0.993331,0.00001285622,0.0007579077,0.0001279953,0.00554349,0.00001960973,0.00006239505,0.000009433394],"genre_scores_gemma":[0.00002199098,0.9963673,0.002067812,0.000439878,0.0004235639,0.0002573423,0.0002450125,0.0001147366,0.00006241504],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.7795576,"threshold_uncertainty_score":0.9997216,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03491260116641351,"score_gpt":0.3425098151029302,"score_spread":0.3075972139365167,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}