{"id":"W2894825807","doi":"10.1002/cbic.201800545","title":"Cover Feature: Quick Click: The DNA‐Templated Ligation of 3′‐<i>O</i>‐Propargyl‐ and 5′‐Azide‐Modified Strands Is as Rapid as and More Selective than Ligase (ChemBioChem 19/2018)","year":2018,"lang":"en","type":"article","venue":"ChemBioChem","topic":"Click Chemistry and Applications","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Click chemistry; Azide; Cycloaddition; Propargyl; DNA ligase; Oligonucleotide; Combinatorial chemistry; Chemistry; DNA; Biochemistry; Organic chemistry; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002434507,0.0005042899,0.0004761252,0.00004322588,0.0004444893,0.000107021,0.0004105839,0.0005562546,0.0003819305],"category_scores_gemma":[0.0002338252,0.0004332375,0.0001556019,0.0004546316,0.001030872,0.0001413818,0.0002104292,0.0004963533,0.00004413969],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007940737,"about_ca_system_score_gemma":0.0001864128,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001150649,"about_ca_topic_score_gemma":0.000005928173,"domain_scores_codex":[0.9977121,0.00002056187,0.0004987508,0.0009018969,0.0003848156,0.000481918],"domain_scores_gemma":[0.9978322,0.0002096661,0.0004120662,0.0009123887,0.0003065419,0.0003271799],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003060055,0.0001689022,0.0004417411,0.000266173,0.0001855803,0.000003049463,0.002084407,4.048897e-7,0.9803336,0.0001908118,0.0152884,0.0007309082],"study_design_scores_gemma":[0.001683822,0.00009401709,0.0004174387,0.0001267072,0.0001719991,0.0001436238,0.0008698595,0.0001227552,0.9896241,0.0008791437,0.005393528,0.000472971],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9721232,0.001018767,0.0000139411,0.002497514,0.0000343208,0.0003144082,0.0001257564,0.0001245793,0.02374751],"genre_scores_gemma":[0.9929565,0.0003415411,0.00006357182,0.0006572714,0.0003890984,0.0001000676,0.0002404401,0.00005993112,0.005191566],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02083331,"threshold_uncertainty_score":0.9998119,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01310221857790054,"score_gpt":0.2648831123186603,"score_spread":0.2517808937407597,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}