{"id":"W2894825807","doi":"10.1002/cbic.201800545","title":"Cover Feature: Quick Click: The DNA‐Templated Ligation of 3′‐<i>O</i>‐Propargyl‐ and 5′‐Azide‐Modified Strands Is as Rapid as and More Selective than Ligase (ChemBioChem 19/2018)","year":2018,"lang":"en","type":"article","venue":"ChemBioChem","topic":"Click Chemistry and Applications","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Click chemistry; Azide; Cycloaddition; Propargyl; DNA ligase; Oligonucleotide; Combinatorial chemistry; Chemistry; DNA; Biochemistry; Organic chemistry; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001998922,0.001076973,0.0006199979,0.0006936011,0.0004036198,0.0006732941,0.0007899431,0.0008683926,0.3573304],"category_scores_gemma":[0.0003396824,0.0006491319,0.0005664466,0.0004482323,0.0002339783,0.001242927,0.0006686134,0.0009743928,0.1407973],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003404644,"about_ca_system_score_gemma":0.000233826,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002616385,"about_ca_topic_score_gemma":0.0005472998,"domain_scores_codex":[0.9997671,0.000007692365,0.000006228208,0.00005017316,0.0001166677,0.00005209109],"domain_scores_gemma":[0.9998543,0.00002989131,0.00001333438,0.00001636107,0.00002807153,0.00005798003],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003739476,0.0001009282,0.0001322191,0.0004572478,0.00002419101,0.0003987555,0.00003337698,0.0001859479,0.2624215,0.003678769,0.6329262,0.09926698],"study_design_scores_gemma":[0.0001086713,0.0002589098,0.001578242,0.00005046308,0.00002091302,0.00106373,0.00001936988,0.001744933,0.1822797,0.001198913,0.8116249,0.00005113067],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"other","genre_gemma":"empirical","genre_scores_codex":[0.03085057,0.01333821,0.06689599,0.006373116,0.01408781,0.0007129741,0.009189229,0.0306308,0.8279212],"genre_scores_gemma":[0.07557747,0.007983963,0.01360894,0.002053102,0.001957702,0.0003489277,0.006818373,0.002462074,0.8891895],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.3573304,"threshold_uncertainty_score":0.9166902,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01310221857790054,"score_gpt":0.2648831123186603,"score_spread":0.2517808937407597,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}