{"id":"W2894881231","doi":"10.1038/s41565-018-0271-3","title":"A malaria vaccine adjuvant based on recombinant antigen binding to liposomes","year":2018,"lang":"en","type":"article","venue":"Nature Nanotechnology","topic":"Malaria Research and Control","field":"Medicine","cited_by":149,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health","keywords":"Antigen; Immunogenicity; Adjuvant; Reactogenicity; Antibody; Liposome; Malaria vaccine; Plasmodium falciparum; Chemistry; Immunization; Virology; Biology; Molecular biology; Immunology; Biochemistry; Malaria","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.000394996,0.000252313,0.0005267277,0.001074201,0.0001546297,0.00002150501,0.0003730445,0.001300097,0.0006636458],"category_scores_gemma":[0.00161259,0.000191199,0.0001154554,0.001020341,0.00007715293,0.00003633644,0.0001232021,0.001579081,0.000707438],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001355494,"about_ca_system_score_gemma":0.0002140696,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002004586,"about_ca_topic_score_gemma":0.00004985328,"domain_scores_codex":[0.9978985,0.00005879897,0.0002711067,0.0005945211,0.0004203354,0.000756726],"domain_scores_gemma":[0.9984394,0.0001126414,0.00007174521,0.0008476503,0.0002776008,0.000250951],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01031912,0.00105735,0.009272327,0.0001299496,0.0003164857,0.001234503,0.00008175299,0.000004141966,0.7191615,0.05170992,0.04625865,0.1604543],"study_design_scores_gemma":[0.01451997,0.01688415,0.04943851,0.000625349,0.0001296307,0.0002736786,0.00006819123,0.003749161,0.5246808,0.001523446,0.3873771,0.0007300226],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6875212,0.0006773266,0.00130485,0.3026386,0.001545944,0.002059904,0.00002576374,0.0007610784,0.003465354],"genre_scores_gemma":[0.9904206,0.00003597878,0.002449247,0.005397719,0.0003379685,0.00007217095,0.00002164305,0.0000421139,0.001222573],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3411184,"threshold_uncertainty_score":0.9999964,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007474110160150437,"score_gpt":0.2885633260706961,"score_spread":0.2810892159105457,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}