{"id":"W2895000731","doi":"10.1055/s-0037-1611053","title":"Directed ortho Metalation (DoM)-Linked Corriu–Kumada, Negishi, and Suzuki–Miyaura Cross-Coupling Protocols: A Comparative Study","year":2018,"lang":"en","type":"article","venue":"Synthesis","topic":"Coordination Chemistry and Organometallics","field":"Chemistry","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Negishi coupling; Chemistry; Metalation; Regioselectivity; Nucleophile; Coupling reaction; Context (archaeology); Combinatorial chemistry; Catalysis; Organic chemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003866342,0.000325142,0.000486674,0.00006938494,0.0004498719,0.0002715263,0.0002609074,0.0001695831,0.003175502],"category_scores_gemma":[0.0007423889,0.0003146353,0.0000957069,0.0003797057,0.0002887058,0.0003056058,0.0001270269,0.000217818,0.00005820395],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000089541,"about_ca_system_score_gemma":0.00006825699,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004653723,"about_ca_topic_score_gemma":0.00007424691,"domain_scores_codex":[0.9981819,0.00002505072,0.0005134612,0.0006093023,0.0003584695,0.0003118286],"domain_scores_gemma":[0.9981623,0.0005166603,0.0003024473,0.0004909644,0.0003890371,0.0001386082],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007933634,0.001769308,0.3563012,0.0005132011,0.0009398634,0.00002394227,0.005874095,0.00006053684,0.6274876,0.0001500267,0.0003755359,0.005711355],"study_design_scores_gemma":[0.001434496,0.0001005241,0.07652076,0.0001666098,0.0002622032,0.00001405303,0.00209949,0.006782576,0.90722,0.0001280154,0.004538666,0.0007325778],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9886647,0.00003327258,0.0000653493,0.00004246574,0.00004352696,0.00207892,0.00003883356,0.0003258357,0.00870705],"genre_scores_gemma":[0.994496,0.000002288525,0.0002712309,0.00001272794,0.0002604681,0.00275058,0.00002295284,0.0000376131,0.002146116],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2797804,"threshold_uncertainty_score":0.9999306,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05616773502349019,"score_gpt":0.3480762606194328,"score_spread":0.2919085255959426,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}