{"id":"W2895079051","doi":"10.1007/s12035-018-1375-3","title":"Early Manifestations of Brain Aging in Mice Due to Low Dietary Folate and Mild MTHFR Deficiency","year":2018,"lang":"en","type":"article","venue":"Molecular Neurobiology","topic":"Folate and B Vitamins Research","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"Canadian Institutes of Health Research","keywords":"Methylenetetrahydrofolate reductase; Endocrinology; Homocysteine; Internal medicine; Cognitive decline; Biology; Choline; Epigenetics; Medicine; Genetics; Genotype; Disease; Dementia; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001533664,0.00009535931,0.0001963062,0.0002660954,0.00003472142,0.000005722603,0.00008751308,0.00006824772,0.00001755088],"category_scores_gemma":[0.0001417844,0.00008786786,0.00003415693,0.0003082798,0.0001478338,0.00002770457,0.00009595043,0.0001539076,0.00003514618],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001120139,"about_ca_system_score_gemma":0.00003798546,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002801667,"about_ca_topic_score_gemma":0.000109047,"domain_scores_codex":[0.999055,0.0001141913,0.0001947339,0.0002799322,0.00007328681,0.000282807],"domain_scores_gemma":[0.9995518,0.00008024622,0.00002751177,0.0001833066,0.00007334151,0.00008377264],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0000833911,0.00007706495,0.006429313,0.00005219646,0.00001180521,0.000723371,0.0004310049,0.000003884228,0.9904902,0.00009992719,0.0001629028,0.001434942],"study_design_scores_gemma":[0.001823486,0.005137522,0.8397295,0.0001407906,0.00003919329,0.0008317561,0.00008536312,0.0003514511,0.1507708,0.0003023515,0.000548729,0.0002390517],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963653,0.0001262073,0.0002231285,0.002260479,0.00005344128,0.0002700555,0.000006522876,0.00001290416,0.0006819327],"genre_scores_gemma":[0.9975749,0.00001485749,0.0004554573,0.001753304,0.00001847225,0.000007148901,0.00001015319,0.0000149254,0.0001507966],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8397194,"threshold_uncertainty_score":0.3583148,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01667127012797345,"score_gpt":0.3003744665036703,"score_spread":0.2837031963756969,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}