{"id":"W2895438005","doi":"10.1093/cid/ciy827","title":"Isavuconazole Versus Caspofungin in the Treatment of Candidemia and Other Invasive Candida Infections: The ACTIVE Trial","year":2018,"lang":"en","type":"article","venue":"Clinical Infectious Diseases","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":178,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network","funders":"Astellas Pharma Global Development; Astellas Pharma; Amplyx; Basilea Pharmaceutica; Astellas Foundation for Research on Metabolic Disorders; Cidara Therapeutics; Teva Pharmaceutical Industries","keywords":"Caspofungin; Medicine; Voriconazole; Clinical endpoint; Population; Internal medicine; Randomized controlled trial; Adverse effect; Surgery; Antifungal","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002476367,0.0009958916,0.002061602,0.0003367682,0.0004027203,0.001313243,0.0007251267,0.001521592,0.00498921],"category_scores_gemma":[0.001989856,0.0003523,0.001968855,0.0003740822,0.0007943704,0.0007868449,0.0003237922,0.002863115,0.0004401901],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000581449,"about_ca_system_score_gemma":0.0009682237,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000573228,"about_ca_topic_score_gemma":0.001335915,"domain_scores_codex":[0.9993018,0.0004304815,0.00005909823,0.000083533,0.00005071933,0.00007437285],"domain_scores_gemma":[0.998795,0.0004258132,0.0003299852,0.00007600024,0.00008835147,0.0002849098],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9497625,0.003319444,0.001129266,0.002170728,0.002104365,0.00005589992,0.00009308931,0.0006478574,0.002101626,0.0003370319,0.001608468,0.03666982],"study_design_scores_gemma":[0.9504902,0.04223019,0.002638759,0.0002490069,0.001578696,0.00008257354,0.00003444988,0.0005589873,0.0004403355,0.0002876345,0.001395458,0.00001372734],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9486911,0.04158846,0.0006681788,0.00197286,0.000846868,0.001788134,0.0009274825,0.00008422556,0.003432698],"genre_scores_gemma":[0.9841888,0.009510098,0.0006441166,0.001177805,0.0008231721,0.001370452,0.0007151792,0.00001364942,0.001556778],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00498921,"threshold_uncertainty_score":0.01669055,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07676338696889055,"score_gpt":0.4163015400127329,"score_spread":0.3395381530438423,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}