{"id":"W2895457918","doi":"10.1101/437459","title":"Condensin II inactivation in interphase does not affect chromatin folding or gene expression","year":2018,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Nautical Research Society","funders":"Deutsche Forschungsgemeinschaft; European Commission; European Molecular Biology Laboratory; Common Fund; Wellcome Trust; National Institutes of Health; National Science Foundation","keywords":"Condensin; Interphase; Chromatin; Mitosis; Cell biology; Biology; Chromosome segregation; Enhancer; Premature chromosome condensation; Gene; CTCF; Genetics; Chromosome; Gene expression; Cohesin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005458349,0.0005707151,0.0005061004,0.0002267433,0.0001788113,0.000138267,0.0005278049,0.0008103413,0.00004145415],"category_scores_gemma":[0.0003387724,0.0004940884,0.0001439105,0.0001909374,0.0001164484,0.00001481006,0.001250691,0.0004121615,0.00001074801],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002417005,"about_ca_system_score_gemma":0.0004394722,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003793323,"about_ca_topic_score_gemma":0.00003063016,"domain_scores_codex":[0.997386,0.0001587952,0.0006164702,0.001110929,0.0002371679,0.0004905717],"domain_scores_gemma":[0.9978287,0.00002945127,0.0005306912,0.001190073,0.0002630063,0.0001581389],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001900366,0.0001494162,0.001370407,0.0002022464,0.00006432639,0.00002512763,0.00001750058,0.00007032971,0.9976691,0.00001515967,0.0002231778,0.000003159691],"study_design_scores_gemma":[0.000855248,0.0002363253,0.008081091,0.000515568,0.00003313045,7.653232e-8,0.000006609348,0.001243564,0.9878022,0.000002748018,0.0005491251,0.0006742845],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957768,0.0001810138,0.002064917,0.00006806403,0.0009458928,0.0006750574,0.000209081,0.0000725227,0.000006590913],"genre_scores_gemma":[0.9871593,0.000188697,0.01153096,0.0001689865,0.0006502489,0.0001388445,0.000007580021,0.0001348872,0.00002046114],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009866883,"threshold_uncertainty_score":0.9997511,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01049488259782142,"score_gpt":0.235399060705045,"score_spread":0.2249041781072236,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}