{"id":"W2895523065","doi":"10.1128/aac.01170-18","title":"Ceftriaxone Absorption Enhancement for Noninvasive Administration as an Alternative to Injectable Solutions","year":2018,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Antibiotics Pharmacokinetics and Efficacy","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Grand Challenges Canada; World Health Organization","keywords":"Bioavailability; Ceftriaxone; Medicine; Absorption (acoustics); Rectal administration; Pharmacology; Pharmacokinetics; Sepsis; Internal medicine; Antibiotics; Biology; Microbiology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003880282,0.0003946059,0.0003106253,0.0003127309,0.00009490195,0.0003713353,0.0003007256,0.0003022942,0.000709088],"category_scores_gemma":[0.0003205812,0.0001559571,0.0002865365,0.0001429871,0.0002653474,0.0004897369,0.0002358798,0.000575189,0.0001943213],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001665617,"about_ca_system_score_gemma":0.0002148244,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002813951,"about_ca_topic_score_gemma":0.0005166351,"domain_scores_codex":[0.9996988,0.00009449245,0.00001280039,0.00004002565,0.0001227363,0.00003125435],"domain_scores_gemma":[0.9998312,0.0000475452,0.00006853498,0.00001746963,0.00001725606,0.0000179365],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003042718,0.0001781858,0.0001560323,0.0001188812,0.000007385781,0.0001066476,0.00002403656,0.0001111329,0.9751675,0.0002454471,0.0001017352,0.02347884],"study_design_scores_gemma":[0.00008710304,0.004701907,0.002209814,0.00003079018,0.00003900347,0.0007661176,0.00002097984,0.00163848,0.9831093,0.00008439121,0.007298963,0.00001314936],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8903445,0.01532014,0.0863369,0.0004958198,0.0001568509,0.0005065111,0.0001275789,0.0003548141,0.006356902],"genre_scores_gemma":[0.9484789,0.007957895,0.03896412,0.0001205834,0.00007346154,0.0001592682,0.00009452487,0.00004348826,0.004107784],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000709088,"threshold_uncertainty_score":0.002372146,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03740218639900309,"score_gpt":0.3435749802606761,"score_spread":0.306172793861673,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}