{"id":"W2895781428","doi":"10.1159/000494759","title":"Palmitate Induces an Anti-Inflammatory Response in Immortalized Microglial BV-2 and IMG Cell Lines that Decreases TNFα Levels in mHypoE-46 Hypothalamic Neurons in Co-Culture","year":2018,"lang":"en","type":"article","venue":"Neuroendocrinology","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Microglia; Endocrinology; TLR4; Internal medicine; Cell culture; Inflammation; Neuroinflammation; Tumor necrosis factor alpha; Biology; Hypothalamus; Receptor; Chemistry; Molecular biology; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003543424,0.0006967683,0.0007264539,0.0004294917,0.0003575159,0.0003333077,0.0003371944,0.0004338144,0.001503329],"category_scores_gemma":[0.0001184375,0.0002493171,0.0006826886,0.0004796919,0.0003404905,0.00020785,0.0002988486,0.0009363587,0.001088368],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002568545,"about_ca_system_score_gemma":0.0002388779,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009277097,"about_ca_topic_score_gemma":0.00152499,"domain_scores_codex":[0.999345,0.00007845773,0.0001026403,0.0001102252,0.000189227,0.0001744009],"domain_scores_gemma":[0.9998286,0.0000214034,0.00004679884,0.00004137103,0.00003248835,0.00002927419],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002406131,0.00008185739,0.0001996239,0.00005957331,0.000008940552,0.00009299839,0.00005213091,0.00003978176,0.9985897,0.00003429412,0.00006468947,0.0005358401],"study_design_scores_gemma":[0.00005915805,0.0008046027,0.006288394,0.00002404855,0.00004290058,0.0006411853,0.0001431931,0.0008318054,0.9875256,0.00007854977,0.003549124,0.00001143291],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9830086,0.004150487,0.006407838,0.0003243249,0.0001632628,0.0001154266,0.002591524,0.0001909053,0.003047659],"genre_scores_gemma":[0.9685633,0.003414827,0.01394029,0.0002726545,0.0001170139,0.0004918582,0.006588936,0.00009346935,0.006517824],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001503329,"threshold_uncertainty_score":0.005029082,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04752615786098258,"score_gpt":0.303075670854003,"score_spread":0.2555495129930204,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}