{"id":"W2895836034","doi":"10.1016/j.jalz.2018.06.1417","title":"P3‐061: CONSTITUTIVE IN VIVO OVEREXPRESSION OF MIR146A AND MIR200B INDEPENDENTLY MODULATES LEVELS OF ALZHEIMER'S DISEASE (AD)‐ RELATED PROTEINS IN THE MOUSE HIPPOCAMPUS AND CEREBRAL CORTEX","year":2018,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Neurological Disease Mechanisms and Treatments","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"London Health Sciences Centre","funders":"","keywords":"Streptozotocin; Hippocampus; Biology; Endocrinology; Genetically modified mouse; microRNA; Cerebral cortex; Internal medicine; Pathology; Transgene; Medicine; Neuroscience; Diabetes mellitus; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000328065,0.0006069425,0.0004867676,0.0004985984,0.0003121465,0.0005347127,0.0004787253,0.0006923691,0.002600553],"category_scores_gemma":[0.0001835035,0.0004019279,0.0005284147,0.0004211718,0.0005418176,0.0004253253,0.0002812162,0.002069458,0.001511212],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004092334,"about_ca_system_score_gemma":0.0004598619,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001179447,"about_ca_topic_score_gemma":0.001515843,"domain_scores_codex":[0.9995146,0.0000466383,0.00006493397,0.0001223843,0.0001379277,0.0001134644],"domain_scores_gemma":[0.9995492,0.00003682603,0.0001222853,0.00004741389,0.00004061764,0.0002036501],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008026369,0.0002599881,0.0001197659,0.00003699449,0.00001122231,0.00004825717,0.00003292768,0.00003570737,0.9976898,0.0001042289,0.0001705571,0.0006878464],"study_design_scores_gemma":[0.0001117175,0.001445166,0.004119159,0.00001022988,0.00003773448,0.0002758825,0.00008177672,0.0008925089,0.9897932,0.00009758426,0.003122446,0.00001263959],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9886611,0.001050961,0.003087733,0.0003887659,0.0001726455,0.0001462992,0.003117687,0.0003602028,0.003014682],"genre_scores_gemma":[0.9742923,0.001283859,0.006677189,0.0003180431,0.00004892222,0.0004651571,0.004272639,0.0002201505,0.01242184],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002600553,"threshold_uncertainty_score":0.008699715,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03330338759218932,"score_gpt":0.2687986216520083,"score_spread":0.235495234059819,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}