{"id":"W2895900900","doi":"10.1152/physiol.00026.2018","title":"Pluripotent Stem Cell-Derived Pancreatic Progenitors and β-Like Cells for Type 1 Diabetes Treatment","year":2018,"lang":"en","type":"review","venue":"Physiology","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Toronto General Hospital; University Health Network","funders":"Toronto General and Western Hospital Foundation; Juvenile Diabetes Research Foundation International","keywords":"Induced pluripotent stem cell; Progenitor cell; Stem cell; Cell; Cell type; SAFER; Pancreas; Biology; In vitro; Cell therapy; In vivo; Type 2 diabetes; Cell biology; Bioinformatics; Diabetes mellitus; Computational biology; Embryonic stem cell; Computer science; Biotechnology; Endocrinology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005225415,0.000693702,0.0006744312,0.001896633,0.0002202881,0.0007012229,0.0006052699,0.0007707524,0.003972125],"category_scores_gemma":[0.0005294065,0.0001983687,0.0003628093,0.001518093,0.0003136783,0.0009418219,0.0006399833,0.001444765,0.002076427],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003077624,"about_ca_system_score_gemma":0.0006415381,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004483769,"about_ca_topic_score_gemma":0.0007507459,"domain_scores_codex":[0.9998484,0.00002222053,0.00002849915,0.00002511048,0.00006296943,0.00001291682],"domain_scores_gemma":[0.9998017,0.00009713299,0.00002739205,0.000007779896,0.00004899408,0.00001697533],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003428452,0.00005878205,0.0001607816,0.01580051,0.00004762576,0.0002422242,0.00007070049,0.0003255506,0.004434927,0.007478062,0.02165505,0.9496914],"study_design_scores_gemma":[0.000005347063,0.00004554892,0.000333558,0.001818418,0.00005158766,0.0008601696,0.0000288581,0.00005459473,0.001134779,0.001440292,0.9942162,0.00001076626],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002114281,0.995967,0.0006022805,0.0003108565,0.0003306748,0.00001213437,0.00004285259,0.00001567168,0.002507092],"genre_scores_gemma":[0.0007432862,0.9976547,0.0004413417,0.0001345626,0.0001204105,0.000009763443,0.00004815089,0.000002275126,0.0008454292],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003972125,"threshold_uncertainty_score":0.01328802,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06502439920473559,"score_gpt":0.3151709222581224,"score_spread":0.2501465230533869,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}