{"id":"W2895927519","doi":"10.1155/2018/3153527","title":"Falcarinol Is a Potent Inducer of Heme Oxygenase‐1 and Was More Effective than Sulforaphane in Attenuating Intestinal Inflammation at Diet‐Achievable Doses","year":2018,"lang":"en","type":"article","venue":"Oxidative Medicine and Cellular Longevity","topic":"Genomics, phytochemicals, and oxidative stress","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Agriculture and Agri-Food Canada; Dalhousie University; Loblaw Companies Limited","keywords":"Sulforaphane; Proinflammatory cytokine; Heme oxygenase; Chemistry; Lipid peroxidation; Pharmacology; Isothiocyanate; HMOX1; Inflammation; Antioxidant; Biochemistry; Immunology; Heme; Biology; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003238013,0.000252993,0.0003694026,0.00009281893,0.0001027388,0.000008573125,0.0001082549,0.0001290374,0.00003020866],"category_scores_gemma":[0.0002982027,0.0002105403,0.00004813068,0.0001389297,0.0007748195,0.00001464048,0.0002710968,0.000146047,0.000002468885],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003000909,"about_ca_system_score_gemma":0.0000237112,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002571439,"about_ca_topic_score_gemma":0.000154153,"domain_scores_codex":[0.9986255,0.0001198664,0.000329985,0.0004976174,0.0001659208,0.0002611183],"domain_scores_gemma":[0.9991507,0.00006187896,0.0002295337,0.000248334,0.0002000599,0.0001094911],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003871549,0.00004504781,0.06574024,0.0001138844,0.000063609,0.000005134259,0.002078599,7.679984e-7,0.9278192,0.00001549682,0.0001228608,0.003608012],"study_design_scores_gemma":[0.001199268,0.001165856,0.07811125,0.0001802705,0.00004534429,0.000009004621,0.001210781,0.0000761625,0.9174143,0.0001124864,0.0002771233,0.0001981503],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961637,0.001887975,0.0005671255,0.0003099903,0.00004594939,0.0004596355,0.00002502033,0.000005840584,0.0005347726],"genre_scores_gemma":[0.9988058,0.0002041324,0.0002810929,0.000112553,0.0002999457,0.00003220194,0.0001276638,0.00001726626,0.0001193135],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01237101,"threshold_uncertainty_score":0.8585583,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0155476176775,"score_gpt":0.2635507737500579,"score_spread":0.2480031560725579,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}