{"id":"W2895981180","doi":"10.1002/anie.201806895","title":"High‐Density RNA Microarrays Synthesized In Situ by Photolithography","year":2018,"lang":"en","type":"article","venue":"Angewandte Chemie International Edition","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Austrian Science Fund; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"RNA; Oligonucleotide; DNA microarray; Phosphoramidite; Phosphodiester bond; DNA; RNase H; Chemistry; RNase P; Nucleotide; Nuclease protection assay; Molecular biology; Combinatorial chemistry; Biochemistry; Biology; Non-coding RNA; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002726629,0.0004592774,0.0003665833,0.0002316948,0.0001766956,0.000468422,0.0003693619,0.0003682753,0.001934645],"category_scores_gemma":[0.0002316681,0.0004315727,0.0002849762,0.0001770619,0.0002660461,0.0003690492,0.0002706391,0.0007828018,0.001390393],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002907097,"about_ca_system_score_gemma":0.000205455,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000148989,"about_ca_topic_score_gemma":0.0004514419,"domain_scores_codex":[0.9997494,0.00004332278,0.00001325399,0.00007069852,0.00008676342,0.00003661304],"domain_scores_gemma":[0.9998784,0.00005231506,0.00002513021,0.00001915065,0.00001468856,0.00001033897],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00000757142,0.000003035608,0.00001372389,0.0000178426,0.000001705385,0.000009015436,0.000005612314,0.00005284748,0.9986851,0.0001464786,0.00003308272,0.001024066],"study_design_scores_gemma":[0.000003045142,0.0000371347,0.0001396542,0.000001983103,0.000004092567,0.00003278904,0.000005104309,0.0006284554,0.9963745,0.00009175022,0.00267814,0.000003286795],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5704195,0.004340317,0.4048115,0.0007053571,0.0003549343,0.0002945221,0.001415941,0.002975042,0.01468282],"genre_scores_gemma":[0.609031,0.00325272,0.3724936,0.0003433601,0.0001292667,0.0004304918,0.001709635,0.0002712288,0.01233877],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001934645,"threshold_uncertainty_score":0.006472051,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007208309446860615,"score_gpt":0.2313846851129651,"score_spread":0.2241763756661045,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}