{"id":"W2896019639","doi":"10.1261/rna.068692.118","title":"Post-transcriptional control of miRNA biogenesis","year":2018,"lang":"en","type":"review","venue":"RNA","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":585,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Medical Research Council; Medical Research Council Canada; Wellcome Trust","keywords":"Drosha; Dicer; Biology; microRNA; Gene silencing; Argonaute; Post-transcriptional regulation; RNA-binding protein; Biogenesis; Regulation of gene expression; Ribonuclease III; Cell biology; Gene expression; RNA-induced silencing complex; Computational biology; RNA; Genetics; RNA interference; Gene; Non-coding RNA","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003698561,0.0006031101,0.0007493839,0.001083163,0.0002444702,0.001051352,0.0006732726,0.0007750405,0.002942069],"category_scores_gemma":[0.0003714681,0.0001837047,0.0002742836,0.00109661,0.0005010931,0.0008668256,0.0006550867,0.001090428,0.002899789],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006023165,"about_ca_system_score_gemma":0.0008157145,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00041217,"about_ca_topic_score_gemma":0.0004686815,"domain_scores_codex":[0.9998218,0.00002684416,0.00002179823,0.00004428164,0.00006243491,0.00002283447],"domain_scores_gemma":[0.9998435,0.0000507488,0.00002959587,0.000008855193,0.00004447614,0.0000229096],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001001036,0.00004347309,0.000334143,0.01156329,0.0000696041,0.0004773429,0.0001033218,0.0004770373,0.02035982,0.02032638,0.02110772,0.9250377],"study_design_scores_gemma":[0.000005639562,0.00003341459,0.0006265585,0.0006782063,0.00002722921,0.001128871,0.00002832397,0.00007933508,0.003531164,0.002388123,0.9914619,0.0000111876],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004982339,0.9928605,0.0008922791,0.0003099177,0.0003704662,0.000008352039,0.00005971504,0.00003235051,0.004968064],"genre_scores_gemma":[0.005192273,0.9909964,0.0006332695,0.0001874487,0.0002315093,0.00001403083,0.0000968507,0.000007988477,0.002640248],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002942069,"threshold_uncertainty_score":0.009842157,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01790409103357319,"score_gpt":0.2829568286532629,"score_spread":0.2650527376196897,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}