{"id":"W2896095031","doi":"10.1007/s00520-018-4515-4","title":"A phase II open-label study of aprepitant as anti-emetic prophylaxis in patients with acute myeloid leukemia (AML) undergoing induction chemotherapy","year":2018,"lang":"en","type":"article","venue":"Supportive Care in Cancer","topic":"Nausea and vomiting management","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; University of Alberta","funders":"Merck Canada","keywords":"Medicine; Aprepitant; Myeloid leukemia; Chemotherapy; Pain medicine; Induction chemotherapy; Oncology; Anesthesia; Internal medicine; Anesthesiology; Antiemetic","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001893699,0.0001994003,0.0004439489,0.0002773644,0.00006901442,0.00001717779,0.0001549848,0.00006685541,0.0001365846],"category_scores_gemma":[0.00004974069,0.0001605032,0.00002139343,0.0006547325,0.0001020633,0.0002060014,0.0001358096,0.0002016379,0.000003490946],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001068466,"about_ca_system_score_gemma":0.0006404835,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001515659,"about_ca_topic_score_gemma":0.002342904,"domain_scores_codex":[0.9983448,0.0000618005,0.0004439803,0.0004766028,0.0003835539,0.000289302],"domain_scores_gemma":[0.998886,0.00001719768,0.0002612904,0.000321672,0.0004468625,0.00006696568],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01110582,0.01440919,0.840819,0.0003998472,0.0007130157,0.0001949582,0.0420127,0.00001180179,0.003966407,0.00002241627,0.0003694,0.08597543],"study_design_scores_gemma":[0.1853727,0.1515932,0.5953596,0.001918984,0.0004239723,0.000004992459,0.03480791,0.00003673083,0.02911084,0.00006838406,0.0006318383,0.0006709262],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959996,0.00005977461,0.000007969172,0.0001227511,0.0001830477,0.002886231,0.00001783614,0.00001839197,0.0007043383],"genre_scores_gemma":[0.999084,0.00005535465,0.0001162816,0.0002137355,0.00007115583,0.0002232785,0.00002553912,0.00003676414,0.0001739076],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2454595,"threshold_uncertainty_score":0.6545132,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02663448780057275,"score_gpt":0.3550497749442467,"score_spread":0.3284152871436739,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}