{"id":"W2896173991","doi":"10.3390/v10100566","title":"Current Perspectives on High-Throughput Sequencing (HTS) for Adventitious Virus Detection: Upstream Sample Processing and Library Preparation","year":2018,"lang":"en","type":"article","venue":"Viruses","topic":"Animal Virus Infections Studies","field":"Agricultural and Biological Sciences","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sanofi (Canada)","funders":"","keywords":"Throughput; Current (fluid); Upstream (networking); Sample (material); DNA sequencing; Computer science; Computational biology; Biology; Engineering; Telecommunications; Chromatography; Genetics; Chemistry; Gene; Electrical engineering","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01304501,0.001403542,0.001394222,0.001099749,0.0008113523,0.004094378,0.003038517,0.004210853,0.007257045],"category_scores_gemma":[0.004915052,0.0006469687,0.001272266,0.001660816,0.002974857,0.007839345,0.001733077,0.003701769,0.002236059],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001665751,"about_ca_system_score_gemma":0.00330806,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001167591,"about_ca_topic_score_gemma":0.002265045,"domain_scores_codex":[0.9957379,0.001662385,0.000260587,0.0006857707,0.001336806,0.0003165601],"domain_scores_gemma":[0.9890866,0.005697453,0.0007994386,0.0006930266,0.002932986,0.0007904968],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0008325965,0.0005426428,0.004030936,0.01250953,0.0002703739,0.0005947337,0.001072773,0.008332722,0.1796973,0.05178519,0.03496608,0.705365],"study_design_scores_gemma":[0.0001623134,0.00318324,0.006335301,0.003290002,0.0004852915,0.001944232,0.002538956,0.02252333,0.1613734,0.09099655,0.7066633,0.0005040618],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"methods","genre_scores_codex":[0.02373059,0.6099083,0.2879673,0.05447619,0.003398721,0.0003691127,0.000526485,0.001077211,0.0185461],"genre_scores_gemma":[0.092016,0.5938737,0.2841232,0.01168861,0.005624151,0.0006629758,0.001431244,0.0003312023,0.010249],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.01304501,"threshold_uncertainty_score":0.0689894,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04672373963354412,"score_gpt":0.2942350930044185,"score_spread":0.2475113533708744,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}