{"id":"W2896211924","doi":"10.1136/annrheumdis-2018-eular.2705","title":"OP0309 Characterisation of clinical benefits in subjects classified as acr20 non-responders at week 104 of apremilast treatment: subanalysis of 3 long-term, phase iii trials","year":2018,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Statistical Methods in Clinical Trials","field":"Mathematics","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Toronto Western Hospital","funders":"Janssen Research and Development; KU Leuven","keywords":"Apremilast; Medicine; Internal medicine; Clinical trial; Term (time); Intensive care medicine; Psoriatic arthritis; Rheumatoid arthritis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01334406,0.00126867,0.004600905,0.0005766233,0.0003990814,0.00162149,0.0009933562,0.001531228,0.002739742],"category_scores_gemma":[0.009400171,0.0005555779,0.007326401,0.001033021,0.001053837,0.001329668,0.0008965135,0.002566908,0.0004328082],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006487818,"about_ca_system_score_gemma":0.0009759041,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004597823,"about_ca_topic_score_gemma":0.001281608,"domain_scores_codex":[0.9920148,0.00548086,0.0007351143,0.0006995431,0.0006494871,0.0004202011],"domain_scores_gemma":[0.9903145,0.00536615,0.002187108,0.001226452,0.0004388452,0.0004669198],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.8743878,0.001338137,0.0414943,0.002340273,0.02721016,0.0001043917,0.0001813301,0.001421319,0.006534509,0.0001896984,0.001267085,0.04353101],"study_design_scores_gemma":[0.3220403,0.1741302,0.4477397,0.0004599135,0.04208567,0.0006873602,0.0003134438,0.003176458,0.002953148,0.001320854,0.004906604,0.00018639],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9787502,0.01435666,0.00147001,0.000410009,0.0001664665,0.0009680394,0.002221935,0.00007359821,0.001582911],"genre_scores_gemma":[0.9939569,0.001265676,0.0008539459,0.0003784172,0.0001285805,0.000736848,0.001998197,0.00002897781,0.0006524383],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01334406,"threshold_uncertainty_score":0.07057101,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.7321362683283751,"score_gpt":0.6138100759340432,"score_spread":0.1183261923943318,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}