{"id":"W2896247465","doi":"10.1002/bdr2.1406","title":"Teratogenicity of valproic acid and its constitutional isomer, amide derivative valnoctamide in mice","year":2018,"lang":"en","type":"article","venue":"Birth Defects Research","topic":"Pharmacological Effects and Toxicity Studies","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Stanley Medical Research Institute","keywords":"Valproic Acid; Fetus; Developmental toxicity; Teratology; Medicine; Internal medicine; Endocrinology; Pregnancy; Andrology; Biology; Pharmacology; Epilepsy; Genetics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002241907,0.0003821381,0.0002883919,0.0008970914,0.0001446898,0.0002534133,0.00024081,0.0003518692,0.001240787],"category_scores_gemma":[0.0001111558,0.0002412245,0.0003204415,0.0002918157,0.0002358269,0.0001693896,0.0001212123,0.0005402307,0.0003041612],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002397243,"about_ca_system_score_gemma":0.0002248689,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006903316,"about_ca_topic_score_gemma":0.0009242724,"domain_scores_codex":[0.9997571,0.00004004922,0.00002826018,0.00006394076,0.00008269816,0.0000279794],"domain_scores_gemma":[0.9997532,0.00003335329,0.0001162465,0.00002867101,0.00002706555,0.00004159522],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002227338,0.00004943815,0.0006174337,0.00002667385,0.00001207531,0.0000665206,0.0000143276,0.0001019636,0.9974486,0.00004739359,0.00003784573,0.001354966],"study_design_scores_gemma":[0.00002653868,0.001357277,0.0064721,0.00001232444,0.00004399699,0.0003536784,0.00002509959,0.0005085751,0.9895984,0.00004163009,0.001554606,0.000005794013],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9896904,0.003278329,0.002386411,0.0001081957,0.00003167732,0.00006478494,0.002115058,0.0001659865,0.002159233],"genre_scores_gemma":[0.9859914,0.00351627,0.002388388,0.00007739429,0.00001531806,0.0001569931,0.002007569,0.00004625427,0.005800419],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001240787,"threshold_uncertainty_score":0.004150867,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1083958924174837,"score_gpt":0.4198709495688349,"score_spread":0.3114750571513512,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}