{"id":"W2896295338","doi":"10.1161/hypertensionaha.118.11775","title":"Pleiotropic Benefits of the Angiotensin Receptor Blocker Candesartan in a Mouse Model of Alzheimer Disease","year":2018,"lang":"en","type":"article","venue":"Hypertension","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Neurological Institute and Hospital","funders":"Canadian Institutes of Health Research; Gladstone Institutes","keywords":"Candesartan; Losartan; Internal medicine; Telmisartan; Endocrinology; Angiotensin II; Medicine; Angiotensin receptor; Blood pressure","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003610621,0.0008259813,0.000871212,0.0008227865,0.0003358304,0.0004265034,0.0004364394,0.0005258296,0.00112867],"category_scores_gemma":[0.0001404603,0.0002304764,0.00047295,0.0002812425,0.0003448553,0.0004223327,0.0002133753,0.002006193,0.0003092861],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002536986,"about_ca_system_score_gemma":0.0005378179,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009398636,"about_ca_topic_score_gemma":0.001938186,"domain_scores_codex":[0.999709,0.00004047761,0.00002813402,0.00005432431,0.0000831469,0.00008486279],"domain_scores_gemma":[0.9997627,0.00001587747,0.00004501034,0.00002663872,0.00002401818,0.0001256217],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002288098,0.0007688624,0.0003334286,0.00008159955,0.00003997713,0.0001632516,0.00002448159,0.0001074484,0.9914726,0.0001586921,0.0001877192,0.004373918],"study_design_scores_gemma":[0.0008746602,0.01511622,0.01952805,0.00004916341,0.0003480597,0.0007290267,0.00009293779,0.001968735,0.955299,0.0003539367,0.005595826,0.00004448581],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9906446,0.002919267,0.002423874,0.0003801494,0.0002008234,0.00008376836,0.0008475819,0.000281441,0.002218481],"genre_scores_gemma":[0.9839101,0.005054163,0.00494691,0.0002557716,0.0001183539,0.0002327135,0.0008712566,0.00006344014,0.004547421],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00112867,"threshold_uncertainty_score":0.003775775,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05225139710549192,"score_gpt":0.2808382946127284,"score_spread":0.2285868975072365,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}