{"id":"W2896329988","doi":"10.1002/cncr.31784","title":"Pregnancies during and after trastuzumab and/or lapatinib in patients with human epidermal growth factor receptor 2–positive early breast cancer: Analysis from the NeoALTTO (BIG 1‐06) and ALTTO (BIG 2‐06) trials","year":2018,"lang":"en","type":"article","venue":"Cancer","topic":"Cancer Risks and Factors","field":"Medicine","cited_by":72,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre intégré de santé et de services sociaux de Chaudière-Appalaches; Hôpital Charles-Le Moyne; Université de Sherbrooke","funders":"","keywords":"Medicine; Lapatinib; Trastuzumab; Pregnancy; Breast cancer; Abortion; Oncology; Internal medicine; Cancer; Obstetrics; Gynecology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001610802,0.0003430304,0.0009391753,0.0001580205,0.0002089184,0.00009052915,0.00008176262,0.000120209,0.0005110617],"category_scores_gemma":[0.00005672011,0.0002004121,0.00009227335,0.0004043109,0.0004062349,0.0001777375,0.0000747505,0.000235969,0.000001544022],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002605779,"about_ca_system_score_gemma":0.0001504631,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.02490995,"about_ca_topic_score_gemma":0.03300032,"domain_scores_codex":[0.9980382,0.0001530108,0.0004875954,0.0006104383,0.000311423,0.0003993423],"domain_scores_gemma":[0.9988524,0.0002000933,0.0002613124,0.0002544776,0.0002032786,0.0002284077],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003355507,0.00005907157,0.9706116,0.00005447286,0.0007243751,0.000005906056,0.006300978,6.338825e-7,0.000294352,0.00000135468,0.00009247631,0.01849928],"study_design_scores_gemma":[0.005847251,0.0004352361,0.9908786,0.000570023,0.0009124606,0.00000227459,0.0002813146,0.000006671233,0.000607487,0.000005654358,0.0001731589,0.0002798593],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935797,0.002201162,0.0000110261,0.0004081417,0.0001386398,0.0008633513,0.002750867,0.00002693415,0.00002012292],"genre_scores_gemma":[0.9972178,0.001010443,0.00003351167,0.0003427184,0.0007949632,0.000292597,0.00005776853,0.00004120346,0.0002089781],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02026702,"threshold_uncertainty_score":0.9846449,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02455567254968904,"score_gpt":0.2851274353830531,"score_spread":0.2605717628333641,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}