{"id":"W2896539080","doi":"10.1016/j.bone.2018.10.012","title":"Abaloparatide, a novel osteoanabolic PTHrP analog, increases cortical and trabecular bone mass and architecture in orchiectomized rats by increasing bone formation without increasing bone resorption","year":2018,"lang":"en","type":"article","venue":"Bone","topic":"Bone health and osteoporosis research","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canadian Nuclear Laboratories","funders":"Radius Health; Harvard School of Dental Medicine","keywords":"Osteoporosis; Bone resorption; Osteopenia; Quantitative computed tomography; Endocrinology; Internal medicine; Medicine; Resorption; Bone remodeling; Cortical bone; Bone mineral; Urology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001578632,0.0005602089,0.000768673,0.001324889,0.0004164201,0.0003818142,0.0004497911,0.000443408,0.002471437],"category_scores_gemma":[0.000139759,0.0004991814,0.000340181,0.0004020929,0.001216384,0.000576839,0.0001964116,0.001183741,0.0003665483],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004379727,"about_ca_system_score_gemma":0.0006525207,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002472761,"about_ca_topic_score_gemma":0.004888881,"domain_scores_codex":[0.999808,0.0000229122,0.00001303622,0.00003918378,0.00006873669,0.00004812747],"domain_scores_gemma":[0.9997038,0.00003306213,0.00009287884,0.00002717718,0.00002566156,0.0001174382],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004311218,0.0003749427,0.0004855741,0.00007142588,0.0000287785,0.00008888247,0.00002744898,0.00009498991,0.9908412,0.0001664281,0.00009108619,0.003418066],"study_design_scores_gemma":[0.0005949108,0.004813606,0.009611511,0.00001056423,0.0001204102,0.0003407958,0.0001157169,0.0007238172,0.9811365,0.0002614268,0.00224659,0.00002425404],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937549,0.002264118,0.001806847,0.0001829751,0.00006229775,0.0000343805,0.0004671106,0.0002328748,0.00119443],"genre_scores_gemma":[0.9880736,0.002607998,0.002694119,0.0001124396,0.00003709985,0.00005973528,0.000645458,0.00007014706,0.005699287],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002472761,"threshold_uncertainty_score":0.00826782,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01751491210867945,"score_gpt":0.3020035929082223,"score_spread":0.2844886807995428,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}