{"id":"W2896579343","doi":"10.1002/cpnc.62","title":"Synthesis of Nucleoside‐5′‐<i>O</i>‐Tetraphosphates from Activated Trimetaphosphate and Nucleoside‐5′‐<i>O</i>‐Monophosphates","year":2018,"lang":"en","type":"article","venue":"Current Protocols in Nucleic Acid Chemistry","topic":"DNA and Nucleic Acid Chemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Nucleoside; Chemistry; Nucleoside analogue; Stereochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000336919,0.000696462,0.0007898963,0.00006874996,0.0001545557,0.00008507907,0.0009017554,0.0005387918,0.0004316244],"category_scores_gemma":[0.0005025648,0.0007131283,0.0002404784,0.0004225588,0.001028022,0.00004581699,0.0005394387,0.0004222566,0.00002229791],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005238194,"about_ca_system_score_gemma":0.0001616684,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004726496,"about_ca_topic_score_gemma":0.000005003412,"domain_scores_codex":[0.9964681,0.00006797684,0.00104021,0.001270901,0.0004027274,0.0007501263],"domain_scores_gemma":[0.9976279,0.0000953179,0.0005678204,0.00114603,0.0002406268,0.0003223705],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007097623,0.0004371251,0.01393337,0.0004156198,0.0001243563,0.000005622352,0.00009908048,0.000001109108,0.9631844,0.00001221609,0.001296626,0.01978075],"study_design_scores_gemma":[0.001815968,0.000163705,0.002686719,0.0007293058,0.0000624198,0.00001035619,0.0001455316,0.00005890616,0.9742553,0.0003196984,0.0190244,0.0007277073],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9897508,0.002811043,0.00002705849,0.00005991031,0.0001647375,0.004747443,0.0001840707,0.00007966081,0.002175281],"genre_scores_gemma":[0.9925475,0.0005889311,0.001138982,0.00007458048,0.0004380509,0.004874841,0.0001100446,0.0001250498,0.0001020092],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01905304,"threshold_uncertainty_score":0.999532,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01147685157020923,"score_gpt":0.2737137075474751,"score_spread":0.2622368559772659,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}