{"id":"W2896611241","doi":"10.1111/ejn.14198","title":"E3 ubiquitin ligases <scp>LNX</scp> 1 and <scp>LNX</scp> 2 localize at neuronal gap junctions formed by connexin36 in rodent brain and molecularly interact with connexin36","year":2018,"lang":"en","type":"article","venue":"European Journal of Neuroscience","topic":"Connexins and lens biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto; SickKids Foundation; University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"NUMB; Ubiquitin ligase; Electrical Synapses; Cell biology; Ubiquitin; PDZ domain; Gap junction; Chemistry; Internalization; Biology; Neuroscience; Intracellular; Biochemistry; Receptor; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001075146,0.0003097089,0.0001868168,0.0001910897,0.0003670013,0.0004052022,0.0001689578,0.0002671056,0.002152199],"category_scores_gemma":[0.0001189497,0.0001454771,0.0003055464,0.0001849876,0.0002362556,0.0002624594,0.0003143076,0.0003554246,0.0005585616],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000506139,"about_ca_system_score_gemma":0.000233453,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009778365,"about_ca_topic_score_gemma":0.001780021,"domain_scores_codex":[0.9998394,0.00001642979,0.00001355359,0.00004608979,0.00005012618,0.00003431033],"domain_scores_gemma":[0.9999162,0.000008540993,0.00002943846,0.000009811395,0.000007446419,0.00002859288],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005297068,0.000009240625,0.001045663,0.00003472951,0.0000105849,0.00007679631,0.00001365628,0.00006371497,0.9976471,0.0002011638,0.00004774234,0.0007966791],"study_design_scores_gemma":[0.000009828587,0.00006407797,0.02781455,0.000009395065,0.00001996649,0.001098708,0.0000545695,0.001448157,0.9639356,0.0001210857,0.005418811,0.000005101329],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947566,0.001613031,0.002182597,0.0001107114,0.00001421973,0.000007562956,0.0003171448,0.0000492195,0.0009488823],"genre_scores_gemma":[0.9907506,0.00113389,0.002870857,0.00004877344,0.000008566511,0.0000165384,0.000868999,0.000009723786,0.004292035],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002152199,"threshold_uncertainty_score":0.007199824,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01486074414191327,"score_gpt":0.2426490587352031,"score_spread":0.2277883145932899,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}