{"id":"W2896731673","doi":"10.1002/jcp.27629","title":"Hypermethylation of ITGBL1 is associated with poor prognosis in acute myeloid leukemia","year":2018,"lang":"en","type":"article","venue":"Journal of Cellular Physiology","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"CAE (Canada)","funders":"China Postdoctoral Science Foundation; Six Talent Peaks Project in Jiangsu Province; National Natural Science Foundation of China","keywords":"Myeloid leukemia; Methylation; DNA methylation; Medicine; Internal medicine; Bisulfite sequencing; Leukemia; Acute promyelocytic leukemia; Bone marrow; Polymerase chain reaction; Oncology; Gastroenterology; Cohort; Biology; Gene expression; Cell culture; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001528619,0.0001718482,0.0002130587,0.0004388138,0.0001272501,0.0002320302,0.0001112793,0.0001495276,0.0007863651],"category_scores_gemma":[0.0003641086,0.00007937862,0.0001206905,0.0004494294,0.0001137861,0.0001102813,0.0001810994,0.0001732982,0.0001278745],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001469163,"about_ca_system_score_gemma":0.00009378676,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007497414,"about_ca_topic_score_gemma":0.001073181,"domain_scores_codex":[0.9999063,0.00002442461,0.000008331617,0.00002485713,0.00001849598,0.00001761428],"domain_scores_gemma":[0.9998422,0.00002433321,0.00008995673,0.000007526714,0.00001448764,0.00002138814],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0009672862,0.00003812437,0.9367098,0.0001000013,0.0001277527,0.0002510679,0.0001302864,0.0002470395,0.04103532,0.00004980927,0.0001923329,0.02015122],"study_design_scores_gemma":[0.00001761618,0.000173797,0.9940829,0.00001152558,0.00009626098,0.0007410278,0.00009812633,0.0006454425,0.003327457,0.00009437104,0.0007070461,0.000004458914],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980177,0.001437299,0.0002217184,0.00003484378,0.00000287119,0.000003064427,0.0001043829,0.000006772139,0.0001714098],"genre_scores_gemma":[0.9991108,0.0003793381,0.0001545381,0.00001959912,0.000006990748,0.000004812985,0.0001603535,0.000001546988,0.0001619835],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007863651,"threshold_uncertainty_score":0.002630651,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01727249031608907,"score_gpt":0.2805497517703246,"score_spread":0.2632772614542355,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}