{"id":"W2896787860","doi":"10.1093/ndt/gfy310","title":"From mice to men: is that fancy new biomarker clinically relevant?","year":2018,"lang":"en","type":"letter","venue":"Nephrology Dialysis Transplantation","topic":"Electrolyte and hormonal disorders","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Medicine; Biomarker; Computational biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005455703,0.0007550767,0.00199268,0.001894738,0.000765231,0.002865183,0.001135467,0.00414543,0.01409635],"category_scores_gemma":[0.01789887,0.0003465247,0.001253985,0.00138931,0.002435166,0.003919709,0.0008618154,0.003209333,0.003602624],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001073873,"about_ca_system_score_gemma":0.001676186,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009595604,"about_ca_topic_score_gemma":0.001784559,"domain_scores_codex":[0.9982917,0.0005025921,0.0002254631,0.0002706347,0.0005733381,0.0001362292],"domain_scores_gemma":[0.9898593,0.006128595,0.001461908,0.0003902083,0.001486192,0.0006738045],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002201097,0.0001052926,0.007924972,0.007183163,0.0006092578,0.003085423,0.0003450923,0.00008258545,0.004574955,0.008911262,0.5377169,0.42726],"study_design_scores_gemma":[0.0003020594,0.0008438841,0.009435348,0.008996895,0.0007561794,0.006165883,0.0004983448,0.0001865463,0.001954545,0.01507079,0.9556905,0.00009907023],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"review","genre_gemma":"commentary","genre_scores_codex":[0.007885967,0.5107966,0.003270919,0.4049531,0.05655958,0.0001875787,0.00204106,0.0004807089,0.01382441],"genre_scores_gemma":[0.08342476,0.4637324,0.005994424,0.3332335,0.09350215,0.000334789,0.001933618,0.0003247019,0.01751964],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.01409635,"threshold_uncertainty_score":0.04715699,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02427044322953476,"score_gpt":0.2964411380333739,"score_spread":0.2721706948038391,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}