{"id":"W2896885793","doi":"10.1007/978-1-4939-8805-1_12","title":"Embryonic Stem Cell Models of Human Brain Tumors","year":2018,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University; University of Manitoba","funders":"","keywords":"Medulloblastoma; Embryonic stem cell; Neural stem cell; Nod; Cancer research; Pathology; Human brain; Biology; Brain tumor; Stem cell; Medicine; Neuroscience; Cell biology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005394447,0.0007207017,0.0003019684,0.001202079,0.0003414805,0.0004995415,0.0007317397,0.0006266008,0.003391686],"category_scores_gemma":[0.0002316818,0.0001893995,0.0003802742,0.0005030967,0.0005645434,0.0004266703,0.0003415582,0.00137103,0.0008042296],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005998225,"about_ca_system_score_gemma":0.0007414671,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001496311,"about_ca_topic_score_gemma":0.00208218,"domain_scores_codex":[0.9996617,0.00007519434,0.00004092251,0.00005354069,0.0001257768,0.00004298802],"domain_scores_gemma":[0.9997873,0.00005215462,0.00003719705,0.00003966076,0.00003504465,0.00004866638],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008961062,0.0005172535,0.0008311507,0.0003948024,0.00007402068,0.001402187,0.0003753796,0.001691794,0.9570032,0.02371704,0.002532795,0.01056425],"study_design_scores_gemma":[0.0001165986,0.0009273472,0.001379159,0.00005575716,0.000120551,0.001527283,0.0001789145,0.002192005,0.9561164,0.002448562,0.03491593,0.00002142089],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.8878922,0.01002265,0.07262445,0.001239989,0.0009641838,0.001268724,0.007658807,0.0006138295,0.01771521],"genre_scores_gemma":[0.9276104,0.01109367,0.02676132,0.000263825,0.00009029856,0.001183494,0.006339803,0.0001229355,0.02653417],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.003391686,"threshold_uncertainty_score":0.01134628,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03512227969895237,"score_gpt":0.3940878073945606,"score_spread":0.3589655276956082,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}