{"id":"W2896909782","doi":"10.1128/mcb.00484-18","title":"Inner Mitochondrial Translocase Tim50 Is Central in Adrenal and Testicular Steroid Synthesis","year":2018,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","keywords":"Biology; Translocase; Inner mitochondrial membrane; Mitochondrial matrix; Pregnenolone; Mitochondrion; Biochemistry; Cholesterol side-chain cleavage enzyme; Cell biology; Steroid biosynthesis; Mitochondrial carrier; ATP–ADP translocase; DNAJA3; mitochondrial fusion; Steroid; Enzyme; Cytochrome P450; Cytosol; Mitochondrial DNA; Bacterial outer membrane; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001825124,0.0004919922,0.0002966775,0.0003086007,0.0005575526,0.0007268799,0.0003382405,0.0006046414,0.004690151],"category_scores_gemma":[0.0002443462,0.000151441,0.0004127134,0.0002950446,0.000396363,0.0005094798,0.0005555112,0.0004129418,0.003098372],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007314128,"about_ca_system_score_gemma":0.0004951846,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007843266,"about_ca_topic_score_gemma":0.0007343695,"domain_scores_codex":[0.9997949,0.00002060603,0.00001755025,0.00006070195,0.0000552619,0.00005094296],"domain_scores_gemma":[0.9997959,0.00001064716,0.00006906565,0.00002249286,0.0000316411,0.00007041985],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003545727,0.00002773536,0.001455329,0.0001578004,0.00001666328,0.0002804487,0.00004920725,0.0001002434,0.9832816,0.001817624,0.0009599309,0.01149895],"study_design_scores_gemma":[0.00004584563,0.0003356709,0.05976334,0.00008694407,0.00008405077,0.002003184,0.0003098885,0.002066927,0.8517385,0.001583005,0.081941,0.00004152589],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9190905,0.0322287,0.02251289,0.001301771,0.0007172123,0.0001121863,0.002726914,0.001804745,0.01950499],"genre_scores_gemma":[0.9759172,0.00423988,0.003108336,0.0001492698,0.00005789179,0.0000354854,0.002120703,0.00008051211,0.01429065],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004690151,"threshold_uncertainty_score":0.01569009,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006944751322012135,"score_gpt":0.2196401507996868,"score_spread":0.2126953994776746,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}