{"id":"W2897004600","doi":"10.1038/s41592-018-0144-6","title":"Transparent Danionella translucida as a genetically tractable vertebrate brain model","year":2018,"lang":"en","type":"article","venue":"Nature Methods","topic":"Single-cell and spatial transcriptomics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":107,"is_retracted":false,"has_abstract":false,"ca_institutions":"Wilfrid Laurier University; University of Ottawa","funders":"","keywords":"Vertebrate; CRISPR; Model organism; Neuroscience; Optogenetics; Biological neural network; Biology; Organism; Zebrafish; Sensory system; Computer science; Computational biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000520152,0.000909773,0.0004507519,0.001283634,0.0008507732,0.0007205451,0.001732122,0.001212751,0.002957021],"category_scores_gemma":[0.0002176125,0.0006481477,0.0007559936,0.0003057087,0.001080062,0.0007333656,0.001105418,0.001853177,0.001098554],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001182341,"about_ca_system_score_gemma":0.0008537084,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004475198,"about_ca_topic_score_gemma":0.01234036,"domain_scores_codex":[0.9995875,0.00003412041,0.00003474205,0.0001181578,0.0001737691,0.00005170176],"domain_scores_gemma":[0.9996982,0.00004974482,0.00009513048,0.00006275754,0.00003261673,0.00006164008],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004902031,0.00001087782,0.00006446106,0.00004046936,0.000006942931,0.00009386572,0.00003029998,0.000212576,0.9968951,0.00190624,0.0001459986,0.0005442965],"study_design_scores_gemma":[0.00008974529,0.0001697924,0.002952086,0.00003471819,0.00009411156,0.0008508566,0.00007085693,0.005835417,0.9714208,0.0008809503,0.01754262,0.00005798117],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8476423,0.002611583,0.1264009,0.001001191,0.0005500975,0.0004769083,0.006856787,0.002231318,0.01222888],"genre_scores_gemma":[0.8637096,0.001644156,0.09074671,0.0002225995,0.00003719813,0.0008008586,0.002982093,0.000976651,0.03888019],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004475198,"threshold_uncertainty_score":0.009892225,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02691576742802112,"score_gpt":0.3679556052443625,"score_spread":0.3410398378163415,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}