{"id":"W2897073164","doi":"10.1021/acs.est.8b04487","title":"Down-Regulation of <i>hspb9</i> and <i>hspb11</i> Contributes to Wavy Notochord in Zebrafish Embryos Following Exposure to Polychlorinated Diphenylsulfides","year":2018,"lang":"en","type":"article","venue":"Environmental Science & Technology","topic":"FOXO transcription factor regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan; Carleton University; Environment and Climate Change Canada","funders":"Anhui Provincial Department of Education; Natural Science Foundation of Anhui Province; China Scholarship Council; National Natural Science Foundation of China; Canada Research Chairs","keywords":"Notochord; Zebrafish; Gene knockdown; Biology; Cell biology; Embryo; Endocrinology; Internal medicine; Anatomy; Embryogenesis; Gene; Genetics; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008420223,0.0002839516,0.0002394274,0.0001775651,0.0001989884,0.0001876599,0.0001164837,0.0002188455,0.001248831],"category_scores_gemma":[0.00007738609,0.0001654304,0.0003229315,0.00009492404,0.0002426748,0.0001435986,0.000242453,0.0004602372,0.0002302359],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002887066,"about_ca_system_score_gemma":0.0002377842,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002161317,"about_ca_topic_score_gemma":0.004131933,"domain_scores_codex":[0.9998982,0.000008330873,0.00001040471,0.0000264636,0.00002827244,0.00002835425],"domain_scores_gemma":[0.9998914,0.000009496216,0.00004336006,0.000008072996,0.00001401604,0.00003361715],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002119138,0.000002259851,0.0001259851,0.00001362921,0.000001387028,0.00002517,0.000004856581,0.00001068625,0.9996351,0.00001155635,0.000009011294,0.0001390099],"study_design_scores_gemma":[0.000007176921,0.0001959981,0.04092231,0.000008239469,0.00001581162,0.000162374,0.00007911945,0.0003523967,0.9567587,0.00002926236,0.001462438,0.000006044046],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956557,0.0008566646,0.001564385,0.0001062454,0.00002493061,0.00002668529,0.0005888848,0.00006312352,0.001113489],"genre_scores_gemma":[0.9946597,0.0006192735,0.0008420592,0.00007220364,0.000004770051,0.00003945495,0.0005160428,0.00001834222,0.003228165],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002161317,"threshold_uncertainty_score":0.004297495,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003915238702878417,"score_gpt":0.2145820565967884,"score_spread":0.21066681789391,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}