{"id":"W2897336854","doi":"10.2217/fmb-2018-0182","title":"Candidate <i>Treponema Pallidum</i> Biomarkers Uncovered in Urine from Individuals with Syphilis Using Mass Spectrometry","year":2018,"lang":"en","type":"article","venue":"Future Microbiology","topic":"Syphilis Diagnosis and Treatment","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria","funders":"National Institute of Allergy and Infectious Diseases; Vlaamse regering; Instituut voor Tropische Geneeskunde","keywords":"Treponema; Syphilis; Urine; Biology; Computational biology; Mass spectrometry; Tandem mass tag; Proteomics; Medicine; Immunology; Gene; Quantitative proteomics; Genetics; Internal medicine; Chemistry; Chromatography","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001589585,0.0003464195,0.0006613641,0.0003199968,0.00007719977,0.0000214686,0.0001390152,0.0002890065,0.001181893],"category_scores_gemma":[0.00002889489,0.0002434325,0.00009632616,0.0005379848,0.0002345567,0.0000534679,0.00006794288,0.0002066214,0.00008983073],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002872247,"about_ca_system_score_gemma":0.0001469583,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001022112,"about_ca_topic_score_gemma":0.002593576,"domain_scores_codex":[0.9982303,0.0001110875,0.0003792438,0.0006587743,0.00009511928,0.0005254492],"domain_scores_gemma":[0.9990007,0.0001087707,0.0001700894,0.0005074647,0.00007897372,0.0001340116],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0005105038,0.0003344478,0.6411335,0.00001987347,0.0008232432,0.000393055,0.0003603116,0.000001341134,0.3534887,0.00002145089,0.002540522,0.0003730592],"study_design_scores_gemma":[0.02155484,0.003947516,0.5702636,0.0007548571,0.001133702,0.001686272,0.001033759,0.00002071549,0.2992409,0.0003720092,0.09882485,0.00116688],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942781,0.001636719,0.00005627714,0.001797492,0.0005709766,0.0005120315,0.0006502208,0.0000521771,0.0004459839],"genre_scores_gemma":[0.982438,0.0001468081,0.01350197,0.001366319,0.001394879,0.0000247473,0.001018381,0.00004699346,0.00006194718],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09628433,"threshold_uncertainty_score":0.9997312,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01022757402401548,"score_gpt":0.2490402629024374,"score_spread":0.2388126888784219,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}