{"id":"W2897336854","doi":"10.2217/fmb-2018-0182","title":"Candidate <i>Treponema Pallidum</i> Biomarkers Uncovered in Urine from Individuals with Syphilis Using Mass Spectrometry","year":2018,"lang":"en","type":"article","venue":"Future Microbiology","topic":"Syphilis Diagnosis and Treatment","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria","funders":"National Institute of Allergy and Infectious Diseases; Vlaamse regering; Instituut voor Tropische Geneeskunde","keywords":"Treponema; Syphilis; Urine; Biology; Computational biology; Mass spectrometry; Tandem mass tag; Proteomics; Medicine; Immunology; Gene; Quantitative proteomics; Genetics; Internal medicine; Chemistry; Chromatography","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000328876,0.0004009486,0.0002918552,0.0009252385,0.0003277624,0.0004864886,0.0001860458,0.0004019768,0.001921614],"category_scores_gemma":[0.0005695829,0.0001126436,0.0002709861,0.0004859454,0.0002139808,0.0001722416,0.0002622511,0.0002020383,0.0003198342],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001770356,"about_ca_system_score_gemma":0.0002094285,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004785212,"about_ca_topic_score_gemma":0.0005229937,"domain_scores_codex":[0.999824,0.00002244446,0.00001750232,0.00005850889,0.00004275302,0.00003476625],"domain_scores_gemma":[0.999827,0.00003341051,0.00007363477,0.000007797802,0.00003212643,0.00002604719],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001630623,0.0002094855,0.2555723,0.0005398631,0.0001566332,0.002017939,0.0003817202,0.000196616,0.7047172,0.0002401423,0.001301557,0.03303588],"study_design_scores_gemma":[0.00007537229,0.001370684,0.6929063,0.0001368493,0.0003924852,0.0104441,0.0005107857,0.0018994,0.2866391,0.0004486637,0.005144922,0.00003130911],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943838,0.001459909,0.001302649,0.0001603519,0.00003444582,0.00003613935,0.00142698,0.00006044774,0.001135235],"genre_scores_gemma":[0.9941128,0.0006105384,0.003620368,0.0001370847,0.00003409173,0.0000193897,0.0009036547,0.0000105525,0.000551525],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001921614,"threshold_uncertainty_score":0.00642848,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01022757402401548,"score_gpt":0.2490402629024374,"score_spread":0.2388126888784219,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}