{"id":"W2897384304","doi":"10.1002/ehf2.12355","title":"Post Hoc Analyses of SHIFT and PARADIGM-HF Highlight the Importance of Chronic Chagas' Cardiomyopathy <i>Comment on:</i> “Safety Profile and Efficacy of Ivabradine in Heart Failure Due to Chagas Heart Disease: A Post Hoc Analysis of the SHIFT Trial” by Bocchi <i>et al.</i>","year":2018,"lang":"en","type":"letter","venue":"ESC Heart Failure","topic":"Trypanosoma species research and implications","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Montreal Heart Institute","funders":"","keywords":"Ivabradine; Medicine; Heart failure; Sacubitril; Internal medicine; Enalapril; Cardiology; Valsartan; Cardiomyopathy; Sacubitril, Valsartan; Post-hoc analysis; Heart rate; Ejection fraction; Angiotensin-converting enzyme; Blood pressure","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.1017565,0.002028874,0.003516376,0.001228831,0.001434834,0.002330819,0.004006261,0.005651951,0.008871951],"category_scores_gemma":[0.2329857,0.0006961703,0.009725614,0.001724682,0.004137073,0.003766405,0.001356824,0.01186076,0.00147012],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001799485,"about_ca_system_score_gemma":0.002189425,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002903268,"about_ca_topic_score_gemma":0.005199949,"domain_scores_codex":[0.9300534,0.04634711,0.006473404,0.004763966,0.01051141,0.001850721],"domain_scores_gemma":[0.5958664,0.3453692,0.01896965,0.0145736,0.02187628,0.003344905],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.03840855,0.0004966513,0.0226413,0.004691137,0.01947977,0.002231791,0.001497064,0.00123265,0.002784948,0.004724292,0.8556442,0.04616764],"study_design_scores_gemma":[0.03263594,0.03128812,0.1896818,0.005344887,0.03674481,0.003698022,0.002373812,0.02971793,0.02124858,0.04276399,0.6028807,0.001621429],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.09147391,0.01929257,0.04330366,0.6248329,0.1817383,0.0060917,0.0167824,0.003780655,0.01270387],"genre_scores_gemma":[0.3626784,0.002577252,0.03162118,0.4979914,0.08468756,0.00741942,0.002645786,0.001250365,0.009128684],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.1017565,"threshold_uncertainty_score":0.5381463,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01431845958848744,"score_gpt":0.3009079960985585,"score_spread":0.2865895365100711,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}