{"id":"W2897385169","doi":"10.2147/ott.s184898","title":"Novel EXO-T vaccine using polyclonal CD4<sup>+</sup> T cells armed with HER2-specific exosomes for HER2-positive breast cancer","year":2018,"lang":"en","type":"review","venue":"OncoTargets and Therapy","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"Saskatchewan Cancer Agency; University of Saskatchewan","funders":"","keywords":"Microvesicles; Polyclonal antibodies; Breast cancer; Medicine; Trastuzumab; Cancer research; Virology; Cancer; Immunology; Antibody; Chemistry; Internal medicine; microRNA; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002490366,0.0004797584,0.0004947645,0.001065809,0.0001509378,0.0004649322,0.0003733353,0.0007860943,0.001606572],"category_scores_gemma":[0.0002408297,0.0001455008,0.0003175206,0.000839492,0.0002299577,0.0007280771,0.0003187985,0.001070942,0.0008356957],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003475901,"about_ca_system_score_gemma":0.0004850788,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003904373,"about_ca_topic_score_gemma":0.0006053552,"domain_scores_codex":[0.9999264,0.00001201009,0.00001006809,0.00001651394,0.0000257683,0.000009224161],"domain_scores_gemma":[0.9999386,0.00002369058,0.00001056476,0.000002153175,0.00001825833,0.000006732153],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001347216,0.000162472,0.0002108297,0.01316877,0.00007927584,0.0003316762,0.00005987006,0.0004651815,0.01209951,0.006285447,0.0256221,0.9413802],"study_design_scores_gemma":[0.00003573241,0.0003334589,0.0006262794,0.001617773,0.00009172306,0.001936869,0.00004879293,0.0002817146,0.00598126,0.001215102,0.9878088,0.00002257216],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0009975706,0.9956922,0.0005311208,0.0004806429,0.0004509454,0.00001653237,0.00002975853,0.00001445386,0.001786895],"genre_scores_gemma":[0.005316382,0.9911164,0.0006156132,0.0004199803,0.000187777,0.00003136259,0.00005742829,0.00000333149,0.002251812],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001606572,"threshold_uncertainty_score":0.005374551,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05716456505432307,"score_gpt":0.3500582671226282,"score_spread":0.2928937020683051,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}