{"id":"W2897385169","doi":"10.2147/ott.s184898","title":"Novel EXO-T vaccine using polyclonal CD4<sup>+</sup> T cells armed with HER2-specific exosomes for HER2-positive breast cancer","year":2018,"lang":"en","type":"review","venue":"OncoTargets and Therapy","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"Saskatchewan Cancer Agency; University of Saskatchewan","funders":"","keywords":"Microvesicles; Polyclonal antibodies; Breast cancer; Medicine; Trastuzumab; Cancer research; Virology; Cancer; Immunology; Antibody; Chemistry; Internal medicine; microRNA; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.0007549826,0.001532874,0.003808056,0.0005611604,0.0004794182,0.0002266417,0.000501229,0.0007421185,0.004619633],"category_scores_gemma":[0.00001042473,0.001045248,0.0009268066,0.0007481132,0.0004368539,0.0002030172,0.000129358,0.0009008133,0.00003281578],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007555957,"about_ca_system_score_gemma":0.001347409,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000299028,"about_ca_topic_score_gemma":0.0001145622,"domain_scores_codex":[0.9942642,0.0002328267,0.001101308,0.001761158,0.001117479,0.001522997],"domain_scores_gemma":[0.9963477,0.0004983228,0.0006279718,0.001041172,0.0007505249,0.0007342869],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.005901874,0.00127746,0.0001093752,0.004655324,0.003675442,0.0001478155,0.0006775534,0.000004040305,0.01438645,0.00008562876,0.005281485,0.9637976],"study_design_scores_gemma":[0.007804323,0.001945475,0.0002103332,0.009913965,0.0006663888,0.001173885,0.00005212192,0.0001192975,0.0005384133,0.00002457225,0.9763497,0.001201561],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.004454851,0.9861975,0.000353317,0.0004991621,0.0005533508,0.005276636,0.001882833,0.0001048816,0.0006774706],"genre_scores_gemma":[0.0001468911,0.9826492,0.003121238,0.000401584,0.004258353,0.0005717891,0.0004877613,0.0005506469,0.007812528],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9710682,"threshold_uncertainty_score":0.999742,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05716456505432307,"score_gpt":0.3500582671226282,"score_spread":0.2928937020683051,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}